About: Amcinonide

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An Entity of Type : yago:WikicatCorticosteroids, within Data Space : wasabi.inria.fr associated with source document(s)

Amcinonide (trade name Cyclocort) is a topical glucocorticoid used to treat itching, redness and swelling associated with several dermatologic conditions such as atopic dermatitis and allergic contact dermatitis.Amcinonide can also be classified as a multi-functional small molecule corticosteroid, which has been approved by the FDA and is currently marketed as an ointment, lotion, or cream. It acts as both a transcription factor for responses to glucocorticoids and modulator for other transcription factors while also regulating phospholipase A2 activity.

Attributes	Values
type	Thing yago:Abstraction100002137 yago:PhysicalEntity100001930 yago:Part113809207 yago:Relation100031921 drug chemical substance drug Chemical object umbel-rc:DrugProduct yago:Chemical114806838 yago:Compound114818238 yago:Material114580897 yago:Matter100020827 yago:OrganicCompound114727670 yago:Substance100019613 yago:Ester114850483 yago:BodySubstance105263850 yago:Corticosteroid114751417 yago:Hormone105407119 yago:LiquidBodySubstance105397468 yago:Secretion105404728 yago:SteroidHormone114745635 yago:WikicatAcetateEsters yago:WikicatCorticosteroids
label	Amcinonide Amcinonid Ancinonida アムシノニド
comment	アムシノニド(Amcinonide)は、アトピー性皮膚炎やアレルギー性接触皮膚炎による痒み、赤み、腫れの治療に用いられる糖質コルチコイド外用薬である。ステロイド外用薬として使われ、日本での格付けで5段階中4のベリーストロング。商標名は、シクロコート(Cyclocort)である。吸収率の高い部位、頬、頭、首、陰部では長期連用しないよう注意し、顔への使用は推奨されない。全米皮膚炎学会によれば、ステロイド外用薬離脱の危険性を医師と患者は知っておきべきで、強いステロイドの連用は2週間までとし、その後少しづつ漸減して減らしていくとした。 Amcinonide (trade name Cyclocort) is a topical glucocorticoid used to treat itching, redness and swelling associated with several dermatologic conditions such as atopic dermatitis and allergic contact dermatitis.Amcinonide can also be classified as a multi-functional small molecule corticosteroid, which has been approved by the FDA and is currently marketed as an ointment, lotion, or cream. It acts as both a transcription factor for responses to glucocorticoids and modulator for other transcription factors while also regulating phospholipase A2 activity. Amcinonid ist ein Arzneistoff der Gruppe der Kortikosteroide mit antiinflammatorischen und antiallergisch wirkenden Eigenschaften. Ancinonida é um fármaco da classe dos corticoides. É de uso tópico.
sameAs	Amcinonide Amcinonide Amcinonide Amcinonide Amcinonide Amcinonide Amcinonide Amcinonide Amcinonide Amcinonide Amcinonide Amcinonide Amcinonide Amcinonide
topic	Corticosteroid dbr:ATC_code_D07 dbr:ATC_code_D07AC11 dbr:ATCvet_code_QD07AC11 dbr:Topical_steroid dbr:List_of_corticosteroid_cyclic_ketals dbr:C28H35FO7 dbr:Cyclocort Cyclopentanonide dbr:List_of_corticosteroid_esters dbr:List_of_corticosteroids dbr:List_of_drugs:_Am wikipedia-en:Amcinonide dbr:Topical_glucocorticoids dbr:Amcinonide#this
depiction
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dbp:drugbank	DB00288
dbp:excretion	Urine and bile
dbp:kegg	D01387
dbp:pregnancyUs	C
dbp:tradename	Cyclocort
Subject	dbc:Fluorinated_corticosteroids Acetate esters Corticosteroids Fluoroarenes Corticosteroid cyclic ketals dbc:Corticosteroid_esters dbc:Cyclopentanonides Pregnanes
dbo:wikiPageID	6718369(xsd:integer)
dbo:wikiPageRevisionID	1084235651(xsd:integer)
dbo:wikiPageWikiLink	Citric acid GlaxoSmithKline American Cyanamid

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