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The lateral hypothalamus (LH), also called the lateral hypothalamic area (LHA), contains the primary orexinergic nucleus within the hypothalamus that widely projects throughout the nervous system; this system of neurons mediates an array of cognitive and physical processes, such as promoting feeding behavior and arousal, reducing pain perception, and regulating body temperature, digestive functions, and blood pressure, among many others. Clinically significant disorders that involve dysfunctions of the orexinergic projection system include narcolepsy, motility disorders or functional gastrointestinal disorders involving visceral hypersensitivity (e.g., irritable bowel syndrome), and eating disorders.

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  • Lateral hypothalamus
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  • الوطاء الجانبي أو تحت المهاد الجانبي (بالإنجليزية: Lateral hypothalamus)‏ يُسمى أيضًا المنطقة الوطائية الجانبية، يحتوي على النواة الأوركسينية بصورة أساسية، المتشعبة في النظام العصبي، ويقوم بعدد من العمليات الإدراكية والجسدية، مثل تعزيز سلوكيات التغذية واليقظة، وتقليل إدراك الألم وتنظيم درجة حرارة الجسم، والوظائف الهضمية وضغط الدم، بين وظائف أخرى عديدة. تشمل الاضطرابات السريرية الناتجة عن اختلال الإسقاط الأوركسيني كل من التغفيق واضطرابات حركة الجهاز الهضمي واضطرابات الجهاز الهضمي الوظيفية ومنها فرط الحساسية الحشوي (مثل متلازمة القولون المتهيج) واضطرابات الأكل.
  • The lateral hypothalamus (LH), also called the lateral hypothalamic area (LHA), contains the primary orexinergic nucleus within the hypothalamus that widely projects throughout the nervous system; this system of neurons mediates an array of cognitive and physical processes, such as promoting feeding behavior and arousal, reducing pain perception, and regulating body temperature, digestive functions, and blood pressure, among many others. Clinically significant disorders that involve dysfunctions of the orexinergic projection system include narcolepsy, motility disorders or functional gastrointestinal disorders involving visceral hypersensitivity (e.g., irritable bowel syndrome), and eating disorders.
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