About: Rapid Identification of Emerging Pathogens: Coronavirus

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Rapid Identification of Emerging Pathogens: Coronavirus Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Rapid Identification of Emerging Pathogens: Coronavirus
Creator	Jiang, Yun Massire, Christian Sampath, Rangarajan Neuman, Benjamin Ranken, Raymond Samant, Vivek Drader, Jared Levene, Harold Blyn, Lawrence Ecker, David Buchmeier, Michael Crooke, Stanley Eshoo, Mark Griffey, Richard Hall, Thomas Hannis, James Harrell, Patina Hofstadler, Steven Mcneil, John
Source	Medline; PMC
abstract	We describe a new approach for infectious disease surveillance that facilitates rapid identification of known and emerging pathogens. The process uses broad-range polymerase chain reaction (PCR) to amplify nucleic acid targets from large groupings of organisms, electrospray ionization mass spectrometry for accurate mass measurements of PCR products, and base composition signature analysis to identify organisms in a sample. We demonstrate this principle by using 14 isolates of 9 diverse Coronavirus spp., including the severe acute respiratory syndrome–associated coronavirus (SARS-CoV). We show that this method could identify and distinguish between SARS and other known CoV, including the human CoV 229E and OC43, individually and in a mixture of all 3 human viruses. The sensitivity of detection, measured by using titered SARS-CoV spiked into human serum, was ≈1 PFU/mL. This approach, applicable to the surveillance of bacterial, viral, fungal, or protozoal pathogens, is capable of automated analysis of >900 PCR reactions per day.
has issue date	2005-03-01(xsd:dateTime)
bibo:doi	10.3201/eid1103.040629
bibo:pmid	15757550
has license	no-cc
sha1sum (hex)	026195c31c1b5e03c8b24560de008bce009e6ada
schema:url	https://doi.org/10.3201/eid1103.040629
resource representing a document's title	Rapid Identification of Emerging Pathogens: Coronavirus
has PubMed Central identifier	PMC3298233
has PubMed identifier	15757550
schema:publication	Emerg Infect Dis
resource representing a document's body	covid:026195c31c1b5e03c8b24560de008bce009e6ada#body_text
is schema:about of	named entity 'disease surveillance' named entity 'targets' named entity 'infectious disease' named entity 'acute' named entity 'Emerging Pathogens' named entity 'Emerging Pathogens' named entity 'pathogens' named entity 'Coronavirus' named entity 'bacterial' named entity 'sample' named entity 'accurate mass' named entity 'automated' named entity 'SARS-CoV' named entity 'respiratory' named entity 'viruses' named entity 'spp' named entity 'emerging pathogens' named entity 'SARS-CoV' named entity 'OC43' named entity 'CoV' named entity 'severe acute respiratory syndrome' named entity 'PCR' named entity 'PCR' named entity 'infectious disease' named entity 'serum' named entity 'Coronavirus' named entity 'genome' named entity 'protozoal' named entity 'HCoV-229E' named entity 'serum' named entity 'HCoV-229E' named entity 'viral genomes' named entity 'SARS-CoV' named entity 'RNA' named entity 'SARS' named entity 'serum' named entity 'enteroviruses' named entity 'mass spectral' named entity 'SARS-CoV' named entity 'primers' named entity 'public health' named entity 'Foster City' named entity 'multiplexed' named entity 'sequence data' named entity 'PCR reaction' named entity 'molecular methods' named entity 'mass spectrometers' named entity 'GenBank' named entity 'U.S.' named entity 'taxonomic' named entity 'animal reservoirs' named entity 'molecular weights' named entity 'PCR reaction' named entity 'electrospray ionization mass spectrometry' named entity 'mutation' named entity 'RNA viruses' named entity 'poly-A' named entity 'GenBank' named entity 'reverse transcription' named entity 'highly conserved' named entity 'mmol/L' named entity 'infectious agents' named entity 'PCR'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software