About: Risk factors for wheezing in a subtropical environment Role of respiratory viruses and allergen sensitization

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Risk factors for wheezing in a subtropical environment Role of respiratory viruses and allergen sensitization
Creator	Arruda, Eurico Platts-Mills, Thomas Chapman, Martin Paulo, São Arruda, L Brazil, Charlottesville Camara, Ataide Cardoso, A Ferriani, Virginia Harsi, Charlotte Macedo, Izolete Padovani, Márcio Preto, Ribeirão Regina, M Silva, Jorgete Tobias, Kátia
topic	covid:03a2f9a8c86cde90a603a64a608290d98fed9aa0#this
source	Elsevier; Medline; PMC
abstract	Abstract Background Risk factors for acute wheezing among children in subtropical areas are largely unknown. Objective To investigate the role of viral infections, allergen sensitization, and exposure to indoor allergens as risk factors for acute wheezing in children 0 to 12 years old. Methods One hundred thirty-two children 0 to 12 years of age who sought emergency department care for wheezing and 65 children with no history of wheezing were enrolled in this case-control study. Detection of respiratory syncytial virus antigen, rhinovirus and coronavirus RNA, adenovirus, influenza, and parainfluenza antigens was performed in nasal washes. Total IgE and specific IgE to mites, cockroach, cat, and dog were measured with the CAP system. Major allergens from mites, cockroach, cat, and dog were quantified in dust samples by ELISA. Univariate and multivariate analyses were performed by logistic regression. Results In children under 2 years of age, infection with respiratory viruses and family history of allergy were independently associated with wheezing (odds ratio, 15.5 and 4.2; P = .0001 and P = .008, respectively). Among children 2 to 12 years old, sensitization to inhalant allergens was the major risk factor for wheezing (odds ratio, 2.7; P = .03). High-level allergen exposure, exposure to tobacco smoke, and lack of breast-feeding showed no association with wheezing. Conclusions Some risk factors for wheezing previously identified in temperate climates were present in a subtropical area, including respiratory syncytial virus infection in infants and allergy in children older than 2 years. Rhinovirus was not associated with wheezing and did not appear to be a trigger for asthma exacerbations.
has issue date	2004-03-31(xsd:dateTime)
bibo:doi	10.1016/j.jaci.2003.11.027
bibo:pmid	15007360
has license	els-covid
sha1sum (hex)	03a2f9a8c86cde90a603a64a608290d98fed9aa0
schema:url	https://doi.org/10.1016/j.jaci.2003.11.027
resource representing a document's title	Risk factors for wheezing in a subtropical environment Role of respiratory viruses and allergen sensitization
has PubMed Central identifier	PMC7127801
has PubMed identifier	15007360
schema:publication	Journal of Allergy and Clinical Immunology
resource representing a document's body	covid:03a2f9a8c86cde90a603a64a608290d98fed9aa0#body_text
is http://vocab.deri.ie/void#inDataset of	https://covidontheweb.inria.fr:4443/about/id/http/ns.inria.fr/covid19/03a2f9a8c86cde90a603a64a608290d98fed9aa0
is schema:about of	named entity 'samples' named entity 'washes' named entity 'mites' named entity 'viral infections' named entity 'odds ratio' named entity 'wheezing' named entity 'areas' named entity 'viruses' named entity 'wheezing' named entity 'environment' named entity 'subtropical' named entity 'ALLERGEN' named entity 'RESPIRATORY SYNCYTIAL VIRUS ANTIGEN' named entity 'OLD' named entity 'LARGELY' named entity 'RISK FACTORS' named entity 'RHINOVIRUS' named entity 'TOTAL IGE' named entity 'CARE' named entity 'YEARS' named entity 'SPECIFIC IGE' named entity 'ACUTE' named entity 'EXPOSURE TO TOBACCO' named entity 'INHALANT' named entity 'RISK FACTORS' named entity 'NO HISTORY OF' named entity '008' named entity 'THIRTY' named entity 'CAP' named entity 'ELISA' named entity 'EMERGENCY DEPARTMENT' named entity 'INFECTION' named entity 'ENROLLED' named entity 'HIGH' named entity 'PERFORMED BY' named entity 'UNDER 2 YEARS' named entity 'DUST' named entity 'INFLUENZA' named entity 'DETECTION' named entity 'OBJECTIVE' named entity 'CHILDREN' named entity 'TO INVESTIGATE' named entity 'METHODS' named entity 'LOGISTIC REGRESSION' named entity 'CASE-CONTROL STUDY' named entity 'SENSITIZATION' named entity 'RESPIRATORY VIRUSES' named entity 'VIRAL INFECTIONS' named entity 'ALLERGY' named entity 'FAMILY HISTORY OF' named entity 'NASAL' named entity 'LACK' named entity 'ROLE' named entity 'EXPOSURE TO' named entity 'LEVEL' named entity 'SUBTROPICAL' named entity '4.2' named entity 'RESULTS' named entity 'UNKNOWN' named entity 'AGE' named entity 'COCKROACH' named entity 'WHEEZING' named entity '2.7' named entity 'BREAST-FEEDING'

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