About: A systematic review on silver nanoparticles-induced cytotoxicity: Physicochemical properties and perspectives

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	A systematic review on silver nanoparticles-induced cytotoxicity: Physicochemical properties and perspectives
Creator	Akter, Mahmuda Banik, Subrata Hosokawa, Toshiyuki Kurasaki, Masaaki Saito, Takeshi Rahman, Md Fatima, Kaniz Hossain, Binte Tajuddin Sikder, Ullah, A
Source	Elsevier; Medline; PMC
abstract	With the development of nanotechnology, silver nanoparticles (Ag-NPs) have become one of the most in-demand nanoparticles owing to their exponential number of uses in various sectors. The increased use of Ag-NPs-enhanced products may result in an increased level of toxicity affecting both the environment and living organisms. Several studies have used different model cell lines to exhibit the cytotoxicity of Ag-NPs, and their underlying molecular mechanisms. This review aimed to elucidate different properties of Ag-NPs that are responsible for the induction of cellular toxicity along with the critical mechanism of action and subsequent defense mechanisms observed in vitro. Our results show that the properties of Ag-NPs largely vary based on the diversified synthesis processes. The physiochemical properties of Ag-NPs (e.g., size, shape, concentration, agglomeration, or aggregation interaction with a biological system) can cause impairment of mitochondrial function prior to their penetration and accumulation in the mitochondrial membrane. Thus, Ag-NPs exhibit properties that play a central role in their use as biocides along with their applicability in environmental cleaning. We herein report a current review of the synthesis, applicability, and toxicity of Ag-NPs in relation to their detailed characteristics.
has issue date	2017-11-02(xsd:dateTime)
bibo:doi	10.1016/j.jare.2017.10.008
bibo:pmid	30046482
has license	cc-by-nc-nd
sha1sum (hex)	05af85c50dd5c80a25fc3dd985d31f0d563d0019
schema:url	https://doi.org/10.1016/j.jare.2017.10.008
resource representing a document's title	A systematic review on silver nanoparticles-induced cytotoxicity: Physicochemical properties and perspectives
has PubMed Central identifier	PMC6057238
has PubMed identifier	30046482
schema:publication	J Adv Res
resource representing a document's body	covid:05af85c50dd5c80a25fc3dd985d31f0d563d0019#body_text
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