About: Chinese and British Hospitalised Patients with COVID-19

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About: Chinese and British Hospitalised Patients with COVID-19—a Comparative Case Series Analysis Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Chinese and British Hospitalised Patients with COVID-19—a Comparative Case Series Analysis
Creator	Raju, S Abdelhafiz, A Broadbent, & Conway, J Emmerton, & Gould, & Khan, & Oklopcic, & Westley, &
Source	Medline; PMC
abstract	The COVID-19 pandemic initially started in China then spread to Europe. It is not known whether COVID-19 affects patients differently across the two continents. We aimed to describe our cohort of patients admitted to a single British centre with COVID-19 in comparison to a Chinese cohort of similar size and admitted over a similar time period to Chinese centres. We present a comparison of 62 Chinese and 71 British cases hospitalised for COVID-19. Cases in both sites were confirmed by a positive RT-PCR of nasopharyngeal swabs. Comparison analysis highlighted some differences between both populations. The most striking difference is the significantly older age of the British population (72% of the British ≥ 66 years compared to only 3% of the Chinese patients, difference of 69%, 95% confidence interval (CI) 68.3% to 69.7%, respectively) and the associated significant premorbid conditions (85% of patients vs 32%, difference of 53%, 95% CI 52 to 54%, respectively). Gastrointestinal and general symptoms were more common clinical presentation in the British while respiratory symptoms were more prominent in the Chinese cohort. Mortality was significantly higher in the British cohort 14% compared to none in the Chinese cohort (difference of 14%, 95% CI 13.7 to 14.3%). We conclude that COVID-19 does present differently in these two cohorts, but the apparent differences in the clinical presentations could be explained by the inherent differences in the demographics and case mix between both countries.
has issue date	2020-07-18(xsd:dateTime)
bibo:doi	10.1007/s42399-020-00414-w
bibo:pmid	32838171
has license	no-cc
sha1sum (hex)	08dd97f6b901ed2b6571346740ed46ad424fe478
schema:url	https://doi.org/10.1007/s42399-020-00414-w
resource representing a document's title	Chinese and British Hospitalised Patients with COVID-19—a Comparative Case Series Analysis
has PubMed Central identifier	PMC7368627
has PubMed identifier	32838171
schema:publication	SN Compr Clin Med
resource representing a document's body	covid:08dd97f6b901ed2b6571346740ed46ad424fe478#body_text
is schema:about of	named entity 'swabs' named entity '95% CI' named entity 'patients' named entity 'cohort' named entity 'RT-PCR' named entity 'Patients' named entity 'ACROSS' named entity 'CASE MIX' named entity 'SITES' named entity 'CONCLUDE' named entity 'CONFIRMED BY' named entity 'YEARS' named entity 'CASE SERIES' named entity 'patients' named entity 'time' named entity 'The' named entity 'Gastrointestinal' named entity 'started' named entity 'comorbidities' named entity 'demographic features' named entity 'Chinese' named entity 'Chinese' named entity 'Chinese' named entity 'Comparison' named entity 'presentations' named entity 'COVID-19' named entity 'clinical presentation' named entity '85%' named entity 'respiratory symptoms' named entity 'Europe' named entity 'COVID-19' named entity 'case mix' named entity 'Italy' named entity 'COVID' named entity 'case series' named entity 'male to female' named entity 'risk factor' named entity 'pneumonia' named entity 'Italy' named entity 'mortality rate' named entity 'COVID' named entity 'chronic obstructive pulmonary disease' named entity 'China' named entity 'fever' named entity 'Italy' named entity 'COVID-19' named entity 'morbidities' named entity 'opioid' named entity 'case fatality rate' named entity 'clinical presentation' named entity 'comorbidity' named entity 'upper respiratory tract' named entity 'clinical presentation' named entity 'comorbidity' named entity 'self-isolation' named entity 'Europe' named entity 'Northern region' named entity 'clinical presentation' named entity 'older people' named entity 'case fatality rates' named entity 'gastrointestinal symptoms' named entity 'China' named entity '95% CI' named entity 'comorbidities' named entity 'COVID' named entity 'confidence interval' named entity 'cardiovascular disease' named entity 'case mix' named entity 'cough' named entity 'liver cirrhosis' named entity 'comorbidity' named entity 'comorbidity' named entity 'risk factor'

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