About: The Role of Anxiety and Cortisol in Outcomes of Patients With Covid-19

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	The Role of Anxiety and Cortisol in Outcomes of Patients With Covid-19
Creator	Hajiesmaeili, Mohammadreza Ramezani, Mahtab Simani, Leila Karimialavijeh, Ehsan Pakdaman, Hossein Rezaei, Omidvar
source	Medline; PMC
abstract	INTRODUCTION: The outbreak due to Coronavirus Disease 2019 (COVID-19) is n global public health emergency and challenges psychological resilience. The central nervous system, endocrine system, and immune system are complex interacting systems. Cortisol has been implicated as the cause of a wide range of mental and physical health disorders; however, the impact of cortisol on outcomes in patients with COVID-19 is not clear. METHODS: The current study enrolled patients with COVID-19 (onset of disease within 7 days of the first symptom) to evaluate the serum concentration of cortisol and levels of anxiety and depression using the Hospital Anxiety and Depression Scale (HADS) to investigate a possible relationship between cortisol, depression, and anxiety levels and outcomes of patients with COVID-19. RESULTS: A total of 30 patients with COVID-19 were studied. The levels of cortisol and HADS score in patients who died of Covid-19 were significantly higher in comparison with surviving patients (P<0.017 and P<0.001 respectively). We also found that the HADS score was positively correlated with serum cortisol levels (r= 0.842, P=0.004). CONCLUSION: Our findings showed that stress and anxiety are associated with patients’ outcomes. Psychological interventions can improve the mental health of vulnerable groups during the COVID-19 epidemic.
has issue date	2020-04-13(xsd:dateTime)
bibo:doi	10.32598/bcn.11.covid19.1168.2
bibo:pmid	32855777
has license	cc-by-nc
sha1sum (hex)	18fcd4d996ad0c9f6a31db8a4f810b9964faaea1
schema:url	https://doi.org/10.32598/bcn.11.covid19.1168.2
resource representing a document's title	The Role of Anxiety and Cortisol in Outcomes of Patients With Covid-19
has PubMed Central identifier	PMC7368100
has PubMed identifier	32855777
schema:publication	Basic Clin Neurosci
resource representing a document's body	covid:18fcd4d996ad0c9f6a31db8a4f810b9964faaea1#body_text
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