About: Factors Predictive of Ventilator-associated Pneumonia in Critically Ill Trauma Patients

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About: Factors Predictive of Ventilator-associated Pneumonia in Critically Ill Trauma Patients Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Factors Predictive of Ventilator-associated Pneumonia in Critically Ill Trauma Patients
Creator	Adamski, • Delozier, Sarah Loudon, • Mcquay, Nathaniel Moorman, Matthew Tinkoff, Glen Uhrises, • Ustin, • Violette, Aisha Younan, Duraid
Source	PMC
abstract	BACKGROUND: Ventilator-associated pneumonia (VAP) is a serious complication of mechanical ventilation. We sought to investigate factors associated with the development of VAP in critically ill trauma patients. METHODS: We conducted a retrospective review of trauma patients admitted to our trauma intensive care unit between 2016 and 2018. Patients with ventilator-associated pneumonia were identified from the trauma database. Data collected from the trauma database included demographics (age, gender and race), mechanism of injury (blunt, penetrating), injury severity (injury severity score “ISS”), the presence of VAP, transfused blood products and presenting vital signs. RESULTS: A total of 1403 patients were admitted to the trauma intensive care unit (TICU) during the study period; of these, 45 had ventilator-associated pneumonia. Patients with VAP were older (p = 0.030), and they had a higher incidence of massive transfusion (p = 0.015) and received more packed cells in the first 24 h of admission (p = 0.028). They had a higher incidence of face injury (p = 0.001), injury to sternum (p = 0.011) and injury to spine (p = 0.024). Patients with VAP also had a higher incidence of acute kidney injury (AKI) (p < 0.001) and had a longer ICU (p < 0.001) and hospital length of stay (p < 0.001). Multiple logistic regression models controlling for age and injury severity (ISS) showed massive transfusion (p = 0.017), AKI (p < 0.001), injury to face (p < 0.001), injury to sternum (p = 0.007), injury to spine (p = 0.047) and ICU length of stay (p < 0.001) to be independent predictors of VAP. CONCLUSIONS: Among critically ill trauma patients, acute kidney injury, injury to the spine, face or sternum, massive transfusion and intensive care unit length of stay were associated with VAP.
has issue date	2019-11-26(xsd:dateTime)
bibo:doi	10.1007/s00268-019-05286-3
bibo:pmid	31773217
has license	no-cc
sha1sum (hex)	253ba2f515e437e821112d17884362e5a5ece631
schema:url	https://doi.org/10.1007/s00268-019-05286-3
resource representing a document's title	Factors Predictive of Ventilator-associated Pneumonia in Critically Ill Trauma Patients
has PubMed Central identifier	PMC7223571
has PubMed identifier	31773217
schema:publication	World J Surg
resource representing a document's body	covid:253ba2f515e437e821112d17884362e5a5ece631#body_text
is schema:about of	named entity 'transfusion' named entity 'spine' named entity 'injury' named entity 'trauma' named entity 'Critically' named entity 'REVIEW OF' named entity 'PACKED CELLS' named entity 'massive' named entity 'vital signs' named entity 'patients' named entity 'length' named entity 'injury' named entity 'VAP' named entity 'trauma' named entity 'length' named entity 'intensive care unit' named entity 'VAP' named entity 'Patients' named entity 'incidence' named entity 'VAP' named entity 'Pneumonia' named entity 'trauma patients' named entity 'sternum' named entity 'injury severity score' named entity 'length of stay' named entity 'VAP' named entity 'ICU' named entity 'acute kidney injury' named entity 'Trauma Patients' named entity 'received' named entity 'complication' named entity 'injury severity score' named entity 'ICU' named entity 'mechanical ventilation' named entity 'physician practice' named entity 'ventilator-associated pneumonia' named entity 'transfusion' named entity 'morbidity' named entity 'transfusion' named entity 'VAP' named entity 'leukopenia' named entity 'VAP' named entity 'attendings' named entity 'ventilator-associated pneumonia' named entity 'ICU' named entity 'intensive care unit' named entity 'ICU' named entity 'critically ill' named entity 'co-morbidities' named entity 'case-control study' named entity 'massive transfusion protocol' named entity 'single center' named entity 'Chest wall' named entity 'AKI' named entity 'morbidity' named entity 'descriptive statistics' named entity 'VAP' named entity 'sternum' named entity 'VAP' named entity 'leukocytosis' named entity 'intensive care unit' named entity 'tertiary care hospital' named entity 'ventilator-associated pneumonia' named entity 'transfusion' named entity 'preventive measures' named entity 'VAP' named entity 'FFP' named entity 'blunt trauma' named entity 'Mann-Whitney U test' named entity 'AKI' named entity 'IRB' named entity 'multivariable analysis'

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