About: An XML-based System for Synthesis of Data from Disparate Databases

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	An XML-based System for Synthesis of Data from Disparate Databases
Creator	Janies, Daniel Camerlengo, Terry Catalyurek, Umit Ervin, David Habib, Farhat Hastings, Shannon Johnson, Andrew Kurc, Tahsin Langella, Stephen Oster, Scott Saltz, Joel
Source	Elsevier; Medline; PMC
abstract	Diverse data sets have become key building blocks of translational biomedical research. Data types captured and referenced by sophisticated research studies include high throughput genomic and proteomic data, laboratory data, data from imagery, and outcome data. In this paper, the authors present the application of an XML-based data management system to support integration of data from disparate data sources and large data sets. This system facilitates management of XML schemas and on-demand creation and management of XML databases that conform to these schemas. They illustrate the use of this system in an application for genotype–phenotype correlation analyses. This application implements a method of phenotype–genotype correlation based on phylogenetic optimization of large data sets of mouse SNPs and phenotypic data. The application workflow requires the management and integration of genomic information and phenotypic data from external data repositories and from the results of phenotype–genotype correlation analyses. Our implementation supports the process of carrying out a complex workflow that includes large-scale phylogenetic tree optimizations and application of Maddison's concentrated changes test to large phylogenetic tree data sets. The data management system also allows collaborators to share data in a uniform way and supports complex queries that target data sets.
has issue date	2006-01-01(xsd:dateTime)
bibo:doi	10.1197/jamia.m1848
bibo:pmid	16501185
has license	no-cc
sha1sum (hex)	256c6b4087d934e17d17a082de1606c3162cd5b3
schema:url	https://doi.org/10.1197/jamia.m1848
resource representing a document's title	An XML-based System for Synthesis of Data from Disparate Databases
has PubMed Central identifier	PMC1513665
has PubMed identifier	16501185
schema:publication	J Am Med Inform Assoc
resource representing a document's body	covid:256c6b4087d934e17d17a082de1606c3162cd5b3#body_text
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