About: Molecular characterization of the 9.36 kb C-terminal region of canine coronavirus 1-71 strain

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About: Molecular characterization of the 9.36 kb C-terminal region of canine coronavirus 1-71 strain Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Molecular characterization of the 9.36 kb C-terminal region of canine coronavirus 1-71 strain
Creator	Lu, Chengping Ae, Wang Ma, Guanggang Yuyan, A
Source	Medline; PMC
abstract	A total of 9.36 kb nucleotides of the C-terminal one-third genome of the canine Coronavirus (CCV) 1-71 strain, including all the structural protein genes and some non-structural protein (nsp) genes were cloned and sequenced. Nucleotide and amino acid sequence alignment as well as phylogenetic analysis of all the structural ORFs with reference coronavirus strains showed that CCV 1-71 was highly related to Chinese CCV isolates. This indicates that these CCV stains may have the same ancestor. Two large deletions were found in ORF3 and led to an elongated nsp3a and a truncated nsp3b. A single “A” insertion in a 6A stretch resulted in the truncation of nsp7b. The great variation in nsp3b and nsp7b indicates that these proteins are not essential for the viral replication.
has issue date	2008-06-01(xsd:dateTime)
bibo:doi	10.1007/s11262-008-0214-4
bibo:pmid	18306032
has license	no-cc
sha1sum (hex)	2f61fc548428f3931e7b1112cdd6c39b1de1c1aa
schema:url	https://doi.org/10.1007/s11262-008-0214-4
resource representing a document's title	Molecular characterization of the 9.36 kb C-terminal region of canine coronavirus 1-71 strain
has PubMed Central identifier	PMC7089161
has PubMed identifier	18306032
schema:publication	Virus Genes
resource representing a document's body	covid:2f61fc548428f3931e7b1112cdd6c39b1de1c1aa#body_text
is schema:about of	named entity 'led' named entity 'Molecular' named entity 'GENES' named entity 'ISOLATES' named entity 'PROTEIN ' named entity 'RELATED' named entity 'CCV' named entity 'ORFS' named entity 'ORF3' named entity 'AMINO ACID SEQUENCE' named entity 'NON-' named entity 'MAY HAVE' named entity 'SEQUENCE ALIGNMENT' named entity 'STRUCTURAL PROTEIN' named entity 'STRAINS' named entity 'VARIATION' named entity 'C-TERMINAL' named entity 'ANCESTOR' named entity 'INSERTION' named entity 'HIGHLY' named entity 'CORONAVIRUS' named entity 'CHINESE' named entity 'SINGLE' named entity 'NUCLEOTIDE' named entity 'STRAIN' named entity 'CHARACTERIZATION' named entity 'NUCLEOTIDES' named entity 'INCLUDING' named entity 'GENOME' named entity 'TRUNCATION' named entity 'GREAT' named entity 'LARGE' named entity 'VIRAL REPLICATION' named entity 'PHYLOGENETIC ANALYSIS' named entity 'STRAIN' named entity 'STRUCTURAL' named entity 'THESE' named entity 'CANINE CORONAVIRUS' named entity '27A' named entity 'REGION' named entity 'ESSENTIAL' named entity 'ELONGATED' named entity 'C-TERMINAL' named entity 'CANINE CORONAVIRUS 1-71' named entity 'FOUND' named entity 'TRUNCATED' named entity 'LED' named entity 'STAINS' named entity 'REFERENCE' named entity 'PROTEINS' named entity 'TOTAL' named entity 'STRETCH' named entity 'MOLECULAR' named entity 'CLONED' covid:arg/2f61fc548428f3931e7b1112cdd6c39b1de1c1aa named entity 'canine' named entity 'isolates' named entity 'ORFs' named entity 'elongated' named entity 'highly' named entity 'genome' named entity 'viral replication' named entity 'nsp' named entity 'nucleotides' named entity 'coronavirus' named entity 'strains' named entity 'gene' named entity 'single-stranded' named entity 'coronavirus' named entity 'canidae' named entity 'glycoprotein' named entity 'coronavirus' named entity 'histologic' named entity 'transmembrane domains' named entity 'protein' named entity 'FIPV' named entity 'Giant Panda' named entity 'protein'

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