About: Epidemiology of seasonal coronaviruses: Establishing the context for COVID-19 emergence

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About: Epidemiology of seasonal coronaviruses: Establishing the context for COVID-19 emergence Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Epidemiology of seasonal coronaviruses: Establishing the context for COVID-19 emergence
Creator	Ho, Antonia Gunson, Rory Nickbakhsh, Sema Murcia, Pablo Diogo, F Marques, Mcmenamin, Jim
topic	covid:336674424facc95d1887f18a9388db508eb94ca8#this
source	MedRxiv
abstract	Public health preparedness for coronavirus disease 2019 (COVID-19) is challenging in the absence of setting-specific epidemiological data. Here we describe the epidemiology of seasonal human coronaviruses (sCoVs) and other cocirculating viruses in the West of Scotland, UK. We analyzed routine diagnostic data for >70,000 episodes of respiratory illness tested molecularly for multiple respiratory viruses between 2005 and 2017. Statistical associations with patient age and sex differed between CoV-229E, CoV-OC43 and CoV-NL63. Furthermore, the timing and magnitude of sCoV outbreaks did not occur concurrently and coinfections were not reported. With respect to other cocirculating respiratory viruses, we found evidence of positive, rather than negative, interactions with sCoVs. These findings highlight the importance of considering cocirculating viruses in the differential diagnosis of COVID-19. Further work is needed to establish the occurrence/degree of cross-protective immunity conferred across sCoVs and with COVID-19, as well as the role of viral coinfection in COVID-19 disease severity.
has issue date	2020-03-20(xsd:dateTime)
bibo:doi	10.1101/2020.03.18.20037101
has license	medrxiv
sha1sum (hex)	336674424facc95d1887f18a9388db508eb94ca8
schema:url	https://doi.org/10.1101/2020.03.18.20037101
resource representing a document's title	Epidemiology of seasonal coronaviruses: Establishing the context for COVID-19 emergence
resource representing a document's body	covid:336674424facc95d1887f18a9388db508eb94ca8#body_text
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