About: Differences in the intestinal microbiota between uninfected piglets and piglets infected with porcine epidemic diarrhea virus

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About: Differences in the intestinal microbiota between uninfected piglets and piglets infected with porcine epidemic diarrhea virus Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Differences in the intestinal microbiota between uninfected piglets and piglets infected with porcine epidemic diarrhea virus
Creator	Wang, Hui Cui, Dong-An Huang, Mei-Zhou Kong, Xiao-Jun Li, Jian-Yong Liu, Xi-Wang Wang, Sheng-Yi Yang, Ya-Jun
Source	PMC
abstract	Porcine epidemic diarrhea, a disastrous gastrointestinal disease, causes great financial losses due to its high infectivity, morbidity and mortality in suckling piglets despite the development and application of various vaccines. In this study, high-throughput sequencing was used to explore differences in the intestinal microbiota between uninfected piglets and piglets infected with porcine epidemic diarrhea virus (PEDV). The results revealed that the small intestinal microbiota of suckling piglets infected with PEDV showed low diversity and was dominated by Proteobacteria (49.1%). Additionally, the composition of the small intestinal microbiota of sucking piglets infected with PEDV showed marked differences from that of the uninfected piglets. Some of the taxa showing differences in abundance between uninfected piglets and piglets infected with PEDV were associated with cellular transport and catabolism, energy metabolism, the biosynthesis of other secondary metabolites, and amino acid metabolism as determined through the prediction of microbial function based on the bacterial 16S rRNA gene. Therefore, adjusting the intestinal microbiota might be a promising method for the prevention or treatment of PEDV.
has issue date	2018-02-15(xsd:dateTime)
bibo:doi	10.1371/journal.pone.0192992
bibo:pmid	29447243
has license	cc-by
sha1sum (hex)	3391fcc4d89196ca239c043cfb37e68d8d2e370a
schema:url	https://doi.org/10.1371/journal.pone.0192992
resource representing a document's title	Differences in the intestinal microbiota between uninfected piglets and piglets infected with porcine epidemic diarrhea virus
has PubMed Central identifier	PMC5814011
has PubMed identifier	29447243
schema:publication	PLoS One
resource representing a document's body	covid:3391fcc4d89196ca239c043cfb37e68d8d2e370a#body_text
is schema:about of	named entity 'INTESTINAL MICROBIOTA' named entity 'gene' named entity 'sucking' named entity 'mortality' named entity 'epidemic' named entity 'Porcine' named entity 'development' named entity 'piglets' covid:arg/3391fcc4d89196ca239c043cfb37e68d8d2e370a named entity 'ENERGY METABOLISM' named entity 'INFECTED' named entity 'CATABOLISM' named entity 'APPLICATION' named entity 'MICROBIAL' named entity 'SECONDARY METABOLITES' named entity 'PREDICTION' named entity 'MARKED' named entity 'METHOD' named entity 'BASED' named entity 'UNINFECTED' named entity 'PROTEOBACTERIA' named entity 'VARIOUS' named entity 'DUE TO' named entity 'COMPOSITION' named entity 'ABUNDANCE' named entity 'BACTERIAL 16S RRNA' named entity 'STUDY' named entity 'VACCINES' named entity 'HIGH' named entity 'RESULTS' named entity 'DEVELOPMENT' named entity 'ITS' named entity 'USED' named entity 'TAXA' named entity 'SMALL INTESTINAL' named entity 'CELLULAR TRANSPORT' named entity 'HIGH-THROUGHPUT SEQUENCING' named entity 'FUNCTION' named entity 'CAUSES' named entity 'UNINFECTED' named entity 'PREVENTION' named entity 'LOW' named entity 'PORCINE EPIDEMIC DIARRHEA VIRUS' named entity 'INFECTED' named entity 'SUCKING' named entity 'ASSOCIATED WITH' named entity 'AMINO ACID METABOLISM' named entity 'INTESTINAL MICROBIOTA' named entity '16S RRNA GENE' named entity 'ADJUSTING' named entity 'TREATMENT' named entity 'PORCINE EPIDEMIC DIARRHEA VIRUS' named entity 'REVEALED' named entity 'FINANCIAL' named entity 'DETERMINED' named entity '2849' named entity 'MORBIDITY AND MORTALITY' named entity 'GREAT' named entity 'PORCINE EPIDEMIC DIARRHEA' named entity 'INFECTIVITY' named entity 'BIOSYNTHESIS' named entity 'DIVERSITY' named entity 'MIGHT BE' named entity 'GASTROINTESTINAL DISEASE' named entity 'piglets' named entity 'piglets' named entity 'piglets' named entity 'catabolism' named entity 'application' named entity 'infected' named entity 'based' named entity 'piglets' named entity 'infectivity' named entity 'piglets'

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