About: Characteristics and outcomes of bacteremia among ICU-admitted patients with severe sepsis

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About: Characteristics and outcomes of bacteremia among ICU-admitted patients with severe sepsis Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Characteristics and outcomes of bacteremia among ICU-admitted patients with severe sepsis
Creator	Sasaki, Junichi Shiino, Yasukazu Kushimoto, Shigeki Fujishima, Seitaro Hifumi, Toru Komori, Akira Kotani, Joji Nakada, Taka-Aki Ogura, Hiroshi Okamoto 15, Kohji Otomo 14, Yasuhiro Saitoh, Daizoh Sakamoto, Yuichiro Shiraishi, Atsushi Umemura, Yutaka
Source	PMC
abstract	The clinical implications of bacteremia among septic patients remain unclear, although a vast amount of data have been accumulated on sepsis. We aimed to compare the clinical characteristics and outcomes of severe sepsis patients with and without bacteremia. This secondary analysis of a multicenter, prospective cohort study included 59 intensive care units (ICUs) in Japan between January 2016 and March 2017. The study cohort comprised 1,184 adults (aged ≥ 16 years) who were admitted to an ICU with severe sepsis and diagnosed according to the Sepsis-2 criteria. Of 1,167 patients included in the analysis, 636 (54.5%) had bacteremia. Those with bacteremia had significantly higher rates of septic shock (66.4% vs. 58.9%, p = 0.01) and higher sepsis severity scores, including the Acute Physiology and Chronic Health Evaluation (APACHE) II and the Sequential Organ Failure Assessment (SOFA). No significant difference in in-hospital mortality was seen between patients with and without bacteremia (25.6% vs. 21.0%, p = 0.08). In conclusion, half of severe sepsis patients in ICUs have bacteremia. Although patients with bacteremia had more severe state, between-group differences in patient-centered outcomes, such as in-hospital mortality, have not been fully elucidated.
has issue date	2020-02-19(xsd:dateTime)
bibo:doi	10.1038/s41598-020-59830-6
bibo:pmid	32076046
has license	cc-by
sha1sum (hex)	3f34428da2b42e3679fc40b0d60e95b5d93f6799
schema:url	https://doi.org/10.1038/s41598-020-59830-6
resource representing a document's title	Characteristics and outcomes of bacteremia among ICU-admitted patients with severe sepsis
has PubMed Central identifier	PMC7031517
has PubMed identifier	32076046
schema:publication	Sci Rep
resource representing a document's body	covid:3f34428da2b42e3679fc40b0d60e95b5d93f6799#body_text
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