About: The impact of changes in diagnostic testing practices on estimates of COVID-19 transmission in the United States

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About: The impact of changes in diagnostic testing practices on estimates of COVID-19 transmission in the United States Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	The impact of changes in diagnostic testing practices on estimates of COVID-19 transmission in the United States
Creator	Cohen, Ted Menzies, Nicolas Pitzer, Virginia Chitwood, Melanie Havumaki, Joshua Perniciaro, Stephanie Warren, Joshua Weinberger, Daniel
source	MedRxiv; Medline; PMC
abstract	Estimates of the reproductive number for novel pathogens such as SARS-CoV-2 are essential for understanding the potential trajectory of the epidemic and the level of intervention that is needed to bring the epidemic under control. However, most methods for estimating the basic reproductive number (R(0)) and time-varying effective reproductive number (R(t)) assume that the fraction of cases detected and reported is constant through time. We explore the impact of secular changes in diagnostic testing and reporting on estimates of R(0) and R(t) using simulated data. We then compare these patterns to data on reported cases of COVID-19 and testing practices from different United States (US) states. We find that changes in testing practices and delays in reporting can result in biased estimates of R(0) and R(t). Examination of changes in the daily number of tests conducted and the percent of patients testing positive may be helpful for identifying the potential direction of bias. Changes in diagnostic testing and reporting processes should be monitored and taken into consideration when interpreting estimates of the reproductive number of COVID-19.
has issue date	2020-04-24(xsd:dateTime)
bibo:doi	10.1101/2020.04.20.20073338
bibo:pmid	32511624
has license	cc-by
sha1sum (hex)	3f40c61d9ead0ffddfd0fd2bdb2e59343ca7ebb5
schema:url	https://doi.org/10.1101/2020.04.20.20073338
resource representing a document's title	The impact of changes in diagnostic testing practices on estimates of COVID-19 transmission in the United States
has PubMed Central identifier	PMC7276051
has PubMed identifier	32511624
schema:publication	medRxiv
resource representing a document's body	covid:3f40c61d9ead0ffddfd0fd2bdb2e59343ca7ebb5#body_text
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