About: Research Progress of Oxidative Stress and MicroRNAs in the Prevention of Catheter-Related Thrombus Under Resistance Exercise

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Research Progress of Oxidative Stress and MicroRNAs in the Prevention of Catheter-Related Thrombus Under Resistance Exercise
Creator	Wen, Cui Ying, Yanping Yu, Fu Zhou, Jianpeng
source	PMC
abstract	Central venous access devices (CVADs) have completely changed the care for patients who require long-term venous access. With the widespread use of CVADs, the incidence of catheter-related thrombus (CRT) has increased. Catheter-related thrombus is a common complication in patients who use CVADs and is mainly caused by endothelial injury, blood stasis, and hypercoagulability. In recent years, the correlations between oxidative stress (OS) and microRNA (miRNA) and CRT have become a hot topic in clinical research. When a catheter punctures the vessel wall, it causes OS damage to the vascular endothelial cells, leading to a series of CRT diseases. MicroRNAs can regulate the mechanism of thrombus and play an important role in the formation of anti-thrombus. Numerous studies have shown that resistance exercise can reduce the level of OS in vascular endothelial cells, inhibit vascular endothelial cell dysfunction, and maintain the stability of hemodynamics and biochemical state. In the current work, the recent studies on the effects of resistance exercise on OS and miRNA in vascular endothelial cells were reviewed.
has issue date	2020-06-15(xsd:dateTime)
bibo:doi	10.1177/1076029620931931
bibo:pmid	32539445
has license	cc-by-nc
sha1sum (hex)	3ffc77bfe86927edb39bb5ec1abbc47703e5ef7a
schema:url	https://doi.org/10.1177/1076029620931931
resource representing a document's title	Research Progress of Oxidative Stress and MicroRNAs in the Prevention of Catheter-Related Thrombus Under Resistance Exercise
has PubMed Central identifier	PMC7427020
has PubMed identifier	32539445
schema:publication	Clin Appl Thromb Hemost
resource representing a document's body	covid:3ffc77bfe86927edb39bb5ec1abbc47703e5ef7a#body_text
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