About: Should We Perform Old-For-Old Kidney Transplantation during the COVID-19 Pandemic? The Risk for Post-Operative Intensive Stay

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Should We Perform Old-For-Old Kidney Transplantation during the COVID-19 Pandemic? The Risk for Post-Operative Intensive Stay
Creator	Ritschl, Paul Schlomm, Thorsten Friedersdorff, Frank Budde, Klemens El-Bandar, Nasrin Liefeldt, Lutz Mihm, Janine Saar, Matthias Sester, Urban Stöckle, Michael Zeuschner, Philip Zompolas, Ilias
Source	Medline; PMC
abstract	Health care systems worldwide have been facing major challenges since the outbreak of the SARS-CoV-2 pandemic. Kidney transplantation (KT) has been tremendously affected due to limited personal protective equipment (PPE) and intensive care unit (ICU) capacities. To provide valid information on risk factors for ICU admission in a high-risk cohort of old kidney recipients from old donors in the Eurotransplant Senior Program (ESP), we retrospectively conducted a bi-centric analysis. Overall, 17 (16.2%) patients out of 105 KTs were admitted to the ICU. They had a lower BMI, and both coronary artery disease (CAD) and hypertensive nephropathy were more frequent. A risk model combining BMI, CAD and hypertensive nephropathy gained a sensitivity of 94.1% and a negative predictive value of 97.8%, rendering it a valuable search test, but with low specificity (51.1%). ICU admission also proved to be an excellent parameter identifying patients at risk for short patient and graft survivals. Patients admitted to the ICU had shorter patient (1-year 57% vs. 90%) and graft (5-year 49% vs. 77%) survival. To conclude, potential kidney recipients with a low BMI, CAD and hypertensive nephropathy should only be transplanted in the ESP in times of SARS-CoV-2 pandemic if the local health situation can provide sufficient ICU capacities.
has issue date	2020-06-12(xsd:dateTime)
bibo:doi	10.3390/jcm9061835
bibo:pmid	32545566
has license	cc-by
sha1sum (hex)	433937a97ae51dd03441c7a02b3a72c60daec558
schema:url	https://doi.org/10.3390/jcm9061835
resource representing a document's title	Should We Perform Old-For-Old Kidney Transplantation during the COVID-19 Pandemic? The Risk for Post-Operative Intensive Stay
has PubMed Central identifier	PMC7356807
has PubMed identifier	32545566
schema:publication	J Clin Med
resource representing a document's body	covid:433937a97ae51dd03441c7a02b3a72c60daec558#body_text
is schema:about of	named entity 'excellent' named entity 'identifying' named entity 'coronary artery disease' named entity 'short' named entity 'hypertensive nephropathy' named entity 'worldwide' named entity 'test' named entity 'sensitivity' named entity 'Program' named entity 'kidney' named entity 'ICU' named entity 'intensive care unit (ICU)' named entity 'Transplantation' named entity 'hypertensive nephropathy' named entity 'high-risk' named entity 'CAD' named entity 'lower BMI' named entity 'Kidney transplantation' named entity 'coronary artery disease' named entity 'hypertensive nephropathy' named entity 'ICU' named entity 'hypertensive nephropathy' named entity 'prednisolone' named entity 'Armonk' named entity 'transplantations' named entity 'univariate analysis' named entity 'serum creatinine' named entity 'FNR' named entity 'transplant surgeons' named entity 'BMI' named entity 'kidney transplantation' named entity 'long-lasting' named entity 'elective surgery' named entity 'risk assessment' named entity 'BMI' named entity 'obesity paradox' named entity 'Mann-Whitney' named entity 'kidney' named entity 'ICU' named entity 'probability' named entity 'patient cohorts' named entity 'infection' named entity 'ICU' named entity 'compartment syndrome' named entity 'induction therapy' named entity 'ICU' named entity 'ICU' named entity 'kidney' named entity 'hazard ratio' named entity 'induction regimen' named entity 'asymptomatic' named entity 'serum creatinine' named entity 'AB0' named entity 'coronary artery disease' named entity 'CAD' named entity 'ICU beds' named entity 'medical staff' named entity 'follow-up' named entity 'medical care' named entity 'organ' named entity 'SARS-CoV-2' named entity 'ICU' named entity 'brain-dead' named entity 'high-risk' named entity 'NPV' named entity 'ICU' named entity 'Kidney Donor' named entity '4.7' named entity 'regression analyses' named entity 'probability'

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