About: Results From the First Six Years of National Sentinel Surveillance for Influenza in Kenya, July 2007

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About: Results From the First Six Years of National Sentinel Surveillance for Influenza in Kenya, July 2007–June 2013 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Results From the First Six Years of National Sentinel Surveillance for Influenza in Kenya, July 2007–June 2013
Creator	Bigogo, Godfrey Feikin, Daniel Mott, Joshua Emukule, Gideon Njuguna, Henry Kalani, Rosalia Muthoka, Philip Katz, Mark Breiman, Robert Ahmed, Jamal Njenga, Moses Waiboci, Lilian
source	PMC
abstract	BACKGROUND: Recent studies have shown that influenza is associated with significant disease burden in many countries in the tropics, but until recently national surveillance for influenza was not conducted in most countries in Africa. METHODS: In 2007, the Kenyan Ministry of Health with technical support from the CDC-Kenya established a national sentinel surveillance system for influenza. At 11 hospitals, for every hospitalized patient with severe acute respiratory illness (SARI), and for the first three outpatients with influenza-like illness (ILI) per day, we collected both nasopharyngeal and oropharyngeal swabs. Beginning in 2008, we conducted in-hospital follow-up for SARI patients to determine outcome. Specimens were tested by real time RT-PCR for influenza A and B. Influenza A-positive specimens were subtyped for H1, H3, H5, and (beginning in May 2009) A(H1N1)pdm09. RESULTS: From July 1, 2007 through June 30, 2013, we collected specimens from 24,762 SARI and 14,013 ILI patients. For SARI and ILI case-patients, the median ages were 12 months and 16 months, respectively, and 44% and 47% were female. In all, 2,378 (9.6%) SARI cases and 2,041 (14.6%) ILI cases were positive for influenza viruses. Most influenza-associated SARI cases (58.6%) were in children <2 years old. Of all influenza-positive specimens, 78% were influenza A, 21% were influenza B, and 1% were influenza A/B coinfections. Influenza circulated in every month. In four of the six years influenza activity peaked during July–November. Of 9,419 SARI patients, 2.7% died; the median length of hospitalization was 4 days. CONCLUSIONS: During six years of surveillance in Kenya, influenza was associated with nearly 10 percent of hospitalized SARI cases and one-sixth of outpatient ILI cases. Most influenza-associated SARI and ILI cases were in children <2 years old; interventions to reduce the burden of influenza, such as vaccine, could consider young children as a priority group.
has issue date	2014-06-23(xsd:dateTime)
bibo:doi	10.1371/journal.pone.0098615
bibo:pmid	24955962
has license	cc0
sha1sum (hex)	458baa469db78afded4d1acdbc4b7d440a5f0a74
schema:url	https://doi.org/10.1371/journal.pone.0098615
resource representing a document's title	Results From the First Six Years of National Sentinel Surveillance for Influenza in Kenya, July 2007–June 2013
has PubMed Central identifier	PMC4067481
has PubMed identifier	24955962
schema:publication	PLoS One
resource representing a document's body	covid:458baa469db78afded4d1acdbc4b7d440a5f0a74#body_text
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