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About:
Suboptimal biological sampling as a probable cause of false-negative COVID-19 diagnostic test results
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schema:ScholarlyArticle
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wasabi.inria.fr
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Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
title
Suboptimal biological sampling as a probable cause of false-negative COVID-19 diagnostic test results
Creator
Stefanovic, Aleksandra
Lowe, Christopher
Jones, R
Brumme, Chanson
Brumme, Zabrina
Dong, Weiyan
Dong, Winnie
Kinloch, Natalie
Lawson, Tanya
Leung, Victor
Matic, Nancy
Montaner, Julio
Ritchie, Gordon
Romney, Marc
source
MedRxiv
abstract
Improper nasopharyngeal swab collection could contribute to false-negative COVID-19 results. In support of this, specimens from confirmed or suspected COVID-19 cases that tested negative or indeterminate (i.e. suspected false-negatives) contained less human DNA (a stable molecular marker of sampling quality) compared to a representative pool of specimens submitted for testing.
has issue date
2020-05-08
(
xsd:dateTime
)
bibo:doi
10.1101/2020.05.05.20091728
has license
medrxiv
sha1sum (hex)
491d6cddfee8cd2a689230283aa9fe790834b670
schema:url
https://doi.org/10.1101/2020.05.05.20091728
resource representing a document's title
Suboptimal biological sampling as a probable cause of false-negative COVID-19 diagnostic test results
resource representing a document's body
covid:491d6cddfee8cd2a689230283aa9fe790834b670#body_text
is
schema:about
of
named entity 'diagnostic test'
named entity 'molecular marker'
named entity 'tested'
named entity 'human'
named entity 'COVID-19'
named entity 'human DNA'
named entity 'COVID-19'
named entity 'tested positive'
named entity 'gene copy number'
named entity 'Virology'
named entity 'nasopharyngeal swab'
named entity 'preprint'
named entity 'diagnostic assays'
named entity 'preprint'
named entity 'preprint'
named entity 'biological sampling'
named entity 'COVID'
named entity 'copy numbers'
named entity 'repeatedly tested'
named entity 'false negative'
named entity 'preprint'
named entity 'RNA'
named entity 'SARS-CoV-2'
named entity 'Canada'
named entity 'primers'
named entity 'medRxiv'
named entity 'RT-PCR'
named entity 'PCR amplification'
named entity 'medRxiv'
named entity 'nested RT-PCR'
named entity 'RNA'
named entity 'tested positive'
named entity 'BioRad'
named entity 'nasopharyngeal swab'
named entity 'CC-BY-ND'
named entity 'SARS-CoV-2'
named entity 'nasopharynx'
named entity 'COVID-19 testing'
named entity 'CC-BY-ND'
named entity 'preprint'
named entity 'human DNA'
named entity 'nasopharyngeal swabs'
named entity 'preprint'
named entity 'false negative'
named entity 'false negative'
named entity 'nested RT-PCR'
named entity 'molecular marker'
named entity 'test sensitivity'
named entity 'PCR-based'
named entity 'CDC'
named entity 'false-negative'
named entity 'preprint'
named entity 'medRxiv'
named entity 'Roche'
named entity 'Poisson statistics'
named entity 'nucleic acid'
named entity 'medRxiv'
named entity 'human genome'
named entity 'preprint'
named entity 'false-negative'
named entity 'COVID-19 testing'
named entity 'Human DNA'
named entity 'COVID-19 test'
named entity 'RNA genome'
named entity 'RNA'
named entity 'infection'
named entity 'CC-BY-ND'
named entity 'gene'
named entity 'biological sampling'
named entity 'public health'
named entity 'RNA'
named entity 'false-negative'
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