About: Towards Wearable and Implantable Continuous Drug Monitoring: A Review

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Towards Wearable and Implantable Continuous Drug Monitoring: A Review
Creator	Sawan, Mohamad Bian, Sumin Rong, Guoguang Sawan, Zhu, Bowen
source	Elsevier; Medline; PMC
abstract	Continuous drug monitoring is a promising alternative to current therapeutic drug monitoring strategies and has strong potential to reshape our understanding of pharmacokinetic variability and to improve individualised therapy. This review highlights recent advances in biosensing technologies that support continuous drug monitoring in real time. We focus primarily on aptamer-based biosensors, wearable and implantable devices. Emphasis is given to the approaches employed in constructing biosensors. We pay attention to sensors’ biocompatibility, calibration performance, long-term characteristics stability and measurement quality. In the end, we discuss about the current challenges and issues to address in continuous drug monitoring to make it a promising, future tool for individualised therapy. The ongoing efforts are expected to result in fully integrated implantable drug biosensing technology. Thus, we may anticipate an era of advanced healthcare in which wearable and implantable biochips automatically adjust drug dosing in response to patient health conditions enabling the management of diseases and enhancing individualised therapy.
has issue date	2020-08-15(xsd:dateTime)
bibo:doi	10.1016/j.jpha.2020.08.001
bibo:pmid	32837742
has license	no-cc
sha1sum (hex)	4c46f436f8d49ff6014583f268500fa9f13c8572
schema:url	https://doi.org/10.1016/j.jpha.2020.08.001
resource representing a document's title	Towards Wearable and Implantable Continuous Drug Monitoring: A Review
has PubMed Central identifier	PMC7428759
has PubMed identifier	32837742
schema:publication	J Pharm Anal
resource representing a document's body	covid:4c46f436f8d49ff6014583f268500fa9f13c8572#body_text
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