About: From Bench to Cageside: Risk Assessment for Rodent Pathogen Contamination of Cells and Biologics

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: From Bench to Cageside: Risk Assessment for Rodent Pathogen Contamination of Cells and Biologics Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	From Bench to Cageside: Risk Assessment for Rodent Pathogen Contamination of Cells and Biologics
Creator	Peterson, Norman
topic	covid:4c5f8cc44f41c073989d4da6e24678c3be538566#this
Source	PMC
abstract	Many newly developed animal models involve the transfer of cells, serum, or other tissue-derived products into live rodents. These biologics can serve as repositories for adventitious rodent pathogens that, when used in animal studies, can alter research outcomes and result in endemic outbreaks. This review includes a description of some of the biologics that have inadvertently introduced infectious agents into in vivo studies and/or resulted in endemic outbreaks. I also discuss the points of potential exposure of specific biologics to adventitious rodent pathogens as well as the importance of acquiring a complete developmental and testing history of each biologic introduced into a barrier facility. There are descriptions of specific cases of mycoplasma and lactate dehydrogenase–elevating virus (LDHV), two of the most common organisms that contaminate cells and cell byproducts. The information in this article should help investigators and animal resource program personnel to perform an appropriate risk assessment of biologics before their use in in vivo studies that involve rodents.
has issue date	2008-01-01(xsd:dateTime)
bibo:doi	10.1093/ilar.49.3.310
bibo:pmid	18506064
has license	no-cc
sha1sum (hex)	4c5f8cc44f41c073989d4da6e24678c3be538566
schema:url	https://doi.org/10.1093/ilar.49.3.310
resource representing a document's title	From Bench to Cageside: Risk Assessment for Rodent Pathogen Contamination of Cells and Biologics
has PubMed Central identifier	PMC7108569
has PubMed identifier	18506064
schema:publication	ILAR J
resource representing a document's body	covid:4c5f8cc44f41c073989d4da6e24678c3be538566#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/4c5f8cc44f41c073989d4da6e24678c3be538566
is schema:about of	named entity 'contaminate' named entity 'infectious agents' named entity 'specific' named entity 'testing' named entity 'specific' named entity 'CONTAMINATION' named entity 'DISCUSS' named entity 'ANIMAL' named entity 'COMMON' named entity 'SERVE' named entity 'COMPLETE' named entity 'HELP' named entity 'RODENT' named entity 'PATHOGENS' named entity 'LACTATE DEHYDROGENASE-ELEVATING VIRUS' named entity 'BARRIER' named entity 'USE' named entity 'HISTORY OF' named entity 'CELLS' named entity 'APPROPRIATE' named entity 'PRODUCTS' named entity 'NEWLY' named entity 'RISK ASSESSMENT' named entity 'INFECTIOUS AGENTS' named entity 'PERSONNEL' named entity 'PROGRAM' named entity 'DEVELOPMENTAL' named entity 'CELLS' named entity 'SPECIFIC' named entity 'POINTS' named entity 'PERFORM' named entity 'ALTER' named entity 'THESE' named entity 'ORGANISMS' named entity 'CELL' named entity 'REPOSITORIES' named entity 'IN VIVO STUDIES' named entity 'ACQUIRING' named entity 'RESULT' named entity 'ANIMAL MODELS ' named entity 'SERUM' named entity 'BIOLOGIC' named entity 'INTRODUCED' named entity 'ANIMAL STUDIES' named entity 'RESOURCE' named entity 'DERIVED' named entity 'RISK ASSESSMENT' named entity 'OF EACH' named entity 'MYCOPLASMA' named entity 'INVESTIGATORS' named entity 'PATHOGEN' named entity 'BIOLOGICS' named entity 'RODENT' named entity 'OUTBREAKS' named entity 'BIOLOGICS' named entity 'RESEARCH' named entity 'TISSUE' named entity 'INTRODUCED INTO' named entity 'FACILITY' named entity 'TRANSFER' named entity 'CONTAMINATE' named entity 'ENDEMIC' named entity 'POTENTIAL' named entity 'OUTCOMES' named entity 'DESCRIPTION' named entity 'USED' named entity 'INFORMATION' named entity 'BENCH' named entity 'TESTING' named entity 'EXPOSURE' named entity 'HAVE' named entity 'REVIEW' named entity 'THEIR' named entity 'ARTICLE' named entity 'RODENTS' named entity 'INCLUDES' named entity 'CASES' named entity 'LIVE' named entity 'rodent'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software