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About:
Efficacy and Safety of Disinfectants for Decontamination of N95 and SN95 Filtering Facepiece Respirators: A Systematic Review
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An Entity of Type :
schema:ScholarlyArticle
, within Data Space :
wasabi.inria.fr
associated with source
document(s)
Type:
Academic Article
research paper
schema:ScholarlyArticle
New Facet based on Instances of this Class
Attributes
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Efficacy and Safety of Disinfectants for Decontamination of N95 and SN95 Filtering Facepiece Respirators: A Systematic Review
Creator
Dayre Mcnally, James
Gertsman, Shira
Gibson, Jess
Lindsey, ;
Mcnally, James
Ng, Rhiannon
O'hearn, Katie
Sampson, Margaret
Sikora, Lindsey
Tsampalieros, Anne
Webster, ;
Webster, Richard
Source
Elsevier; Medline; PMC
abstract
BACKGROUND: Decontaminating and re-using filtering facepiece respirators (FFRs) for healthcare workers is a potential solution to address inadequate FFR supply during a global pandemic. AIM: The objective of this review was to synthesize existing data on the effectiveness and safety of using chemical disinfectants to decontaminate N95 FFRs. METHODS: We conducted a systematic review on disinfectants to decontaminate N95 FFRs using Embase, Medline, Global Health, Google Scholar, WHO feed, and MedRxiv. Two reviewers independently determined study eligibility and extracted predefined data fields. Original research reporting on N95 FFR function, decontamination, safety, or FFR fit following decontamination with a disinfectant was included. FINDINGS AND CONCLUSIONS: A single cycle of vaporized hydrogen peroxide (H(2)O(2)) successfully removes viral pathogens without affecting airflow resistance or fit, and maintains an initial filter penetration of <5%, with little change in FFR appearance. Residual hydrogen peroxide levels following decontamination were within safe limits. More than one decontamination cycle of vaporized H(2)O(2) may be possible but further information is required on how multiple cycles would affect FFR fit in a real world setting before the upper limit can be established. Although immersion in liquid H(2)O(2) does not appear to adversely affect FFR function, there is no available data on its ability to remove infectious pathogens from FFRs or its impact on FFR fit. Sodium hypochlorite, ethanol, isopropyl alcohol and ethylene oxide are not recommended due to safety concerns or negative effects on FFR function.
has issue date
2020-08-13
(
xsd:dateTime
)
bibo:doi
10.1016/j.jhin.2020.08.005
bibo:pmid
32800824
has license
no-cc
sha1sum (hex)
4c72ab599247451b9bc90107f11aeacc33f82c3b
schema:url
https://doi.org/10.1016/j.jhin.2020.08.005
resource representing a document's title
Efficacy and Safety of Disinfectants for Decontamination of N95 and SN95 Filtering Facepiece Respirators: A Systematic Review
has PubMed Central identifier
PMC7423630
has PubMed identifier
32800824
schema:publication
J Hosp Infect
resource representing a document's body
covid:4c72ab599247451b9bc90107f11aeacc33f82c3b#body_text
is
schema:about
of
named entity 'Efficacy'
named entity 'N95'
named entity 'healthcare'
named entity 'workers'
named entity 'Safety'
named entity 'Systematic'
named entity 'Filtering'
named entity 'FFRs'
named entity 'FFR'
named entity 'Systematic Review'
named entity 'N95'
named entity 'Respirators'
named entity 'Respirators'
named entity 'FFRs'
named entity 'meta-analysis'
named entity 'disinfectant'
named entity 'systematic review'
named entity 'disinfectant'
named entity 'disinfectants'
named entity 'Bacillus subtilis'
named entity 'disinfectant'
named entity 'FFRs'
named entity 'disinfectant'
named entity 'bacteriophage'
named entity 'clinical setting'
named entity 'aerosol'
named entity 'sodium hypochlorite'
named entity 'VHP'
named entity 'NIOSH certification'
named entity 'systematic review'
named entity 'disinfectants'
named entity 'PPE'
named entity 'ethanol'
named entity 'hydrogen peroxide'
named entity 'National Institute for Occupational Safety and Health'
named entity 'disinfectant'
named entity 'open-access'
named entity 'ultraviolet germicidal irradiation'
named entity 'control group'
named entity 'standard deviation'
named entity 'germicidal'
named entity 'germicidal'
named entity 'N95'
named entity 'Centres for Disease Control and Prevention'
named entity 'disinfectant'
named entity 'sodium hypochlorite'
named entity 'NIOSH'
named entity 'chlorine'
named entity 'health care workers'
named entity 'vaporized hydrogen peroxide'
named entity 'Heterogeneity'
named entity 'disinfectant'
named entity 'germicidal'
named entity 'FFRs'
named entity 'world conditions'
named entity 'pre-print'
named entity 'aerosol'
named entity 'PPE'
named entity 'aerosol'
named entity 'VSV'
named entity 'aerosol'
named entity 'aerosol'
named entity 'fit test'
named entity 'aerosol'
named entity 'aerosol'
named entity 'selective reporting'
named entity 'disinfectant'
named entity '95% CI'
named entity 'sterilization'
named entity 'peer-reviewed'
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