About: Respiratory Infections

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Respiratory Infections
Creator	Nissen, Michael Sloots, Theo Whiley, David Lambert, Stephen
source	PMC
abstract	Until recently, conventional culture techniques and immunofluorecence assays were considered the gold standard for the detection of respiratory viruses, even though results are mostly available too late or lacked specificity and sensitivity. These methods are now widely replaced with appropriate DNA- and RNA-based amplification techniques, in particular real time PCR amplification, for the detection of an extended number of agents responsible for acute respiratory infections. Real-time PCR offers rapid results, efficiencies in work flow and a reduced risk of false positive results due to contamination. As a result, better patient management or reduction of unnecessary antibiotic administration will be possible leading to enhanced efficiencies in health care. In applying molecular methods to diagnostic use, the laboratory can optimise its diagnostic strategy by applying a combination of real-time amplification tests for respiratory viruses and the non-viral respiratory bacterial pathogens. However this must be done within a context of resource availability, technical expertise available and clinical utility. It seems certain that molecular microbiology will continue to develop, leading to further applications in diagnostic technology, thereby improving our understanding of disease processes and enhancing our knowledge of the pathogens responsible.
has issue date	2010-03-27(xsd:dateTime)
bibo:doi	10.1007/978-90-481-9039-3_5
has license	no-cc
sha1sum (hex)	4d2366b0ee4d6b5ec8c8b7376e7b343fa15e0ff8
schema:url	https://doi.org/10.1007/978-90-481-9039-3_5
resource representing a document's title	Respiratory Infections
has PubMed Central identifier	PMC7193730
schema:publication	PCR for Clinical Microbiology
resource representing a document's body	covid:4d2366b0ee4d6b5ec8c8b7376e7b343fa15e0ff8#body_text
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