About: CORDITE: the curated CORona Drug InTERactions database for SARS-CoV-2

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About: CORDITE: the curated CORona Drug InTERactions database for SARS-CoV-2 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	CORDITE: the curated CORona Drug InTERactions database for SARS-CoV-2
Creator	Martin, R Hattab, G Hattab, Georges Hauschild, A.-C Hauschild, Anne-Christin Heider, Dominik Löchel, H Löchel, Hannah Martin, Roman Welzel, M Welzel, Marius
source	Elsevier; Medline; PMC
abstract	Summary Since the outbreak in 2019, researchers are trying to find effective drugs against the SARS-CoV-2 virus based on de novo drug design and drug repurposing. While the former approach is very time-consuming and needs extensive testing in humans, drug repurposing is more promising, as the drugs have already been tested for side-effects, etc. Currently, there is no treatment for COVID-19 that is clinically effective, but there is a huge amount of data from studies that analyze potential drugs. We developed CORDITE to efficiently combine state-of-the-art knowledge on potential drugs and make it accessible to scientists and clinicians. The web interface also provides access to an easy-to-use API that allows a wide use for other software and applications, e.g., for meta-analysis, design of new clinical studies, or simple literature search. CORDITE is currently empowering many scientists across all continents and accelerates research in the knowledge domains of virology and drug design. Availability: CORDITE is available athttps://cordite.mathematik.uni-marburg.de
has issue date	2020-06-20(xsd:dateTime)
bibo:doi	10.1016/j.isci.2020.101297
bibo:pmid	32619700
has license	els-covid
sha1sum (hex)	52f3259b1cecffb13c8ec572b113744880f2194b
schema:url	https://doi.org/10.1016/j.isci.2020.101297
resource representing a document's title	CORDITE: the curated CORona Drug InTERactions database for SARS-CoV-2
has PubMed Central identifier	PMC7305714
has PubMed identifier	32619700
schema:publication	iScience
resource representing a document's body	covid:52f3259b1cecffb13c8ec572b113744880f2194b#body_text
is schema:about of	named entity 'empowering' named entity 'COVID-19' named entity 'potential' named entity 'Drug' named entity 'HUMANS' named entity 'BASED' named entity 'KNOWLEDGE' named entity 'ACCESSIBLE' named entity 'EFFECTS' named entity 'DE NOVO' named entity 'scientists' named entity 'side-effects' named entity 'researchers' named entity 'efficiently' named entity 'The' named entity 'literature search' named entity 'drug design' named entity 'CORDITE' named entity 'COVID' named entity 'CORDITE' named entity 'SARS-CoV-2' named entity 'Python' named entity 'drug repurposing' named entity 'fatality rate' named entity 'protease' named entity 'spike protein' named entity 'spike protein' named entity 'Lopinavir' named entity 'kidneys' named entity 'liver' named entity 'CORDITE' named entity 'peer-reviewed' named entity 'RNA genome' named entity 'Clinical trials' named entity 'spleen' named entity 'SARS-CoV-2' named entity 'vaccines' named entity 'spike protein' named entity 'clinical trials' named entity 'cell membrane' named entity 'virus' named entity 'human targets' named entity 'shortness of breath' named entity 'COVID' named entity 'clinicaltrials.gov' named entity 'drug interactions' named entity 'toxicity' named entity 'testis' named entity 'CORDITE' named entity 'clinical trials' named entity 'bone marrow' named entity 'Transmembrane' named entity 'approved drugs' named entity 'CORDITE' named entity 'papain' named entity 'CORDITE' named entity 'meta-search engine' named entity 'Biopython' named entity 'CORDITE' named entity 'SARS' named entity 'ACE2' named entity 'meta-analyses' named entity 'methyltransferase' named entity 'drug repurposing' named entity 'PHP' named entity 'SARS' named entity 'SARS-Cov-2' named entity 'preprints' named entity 'dyspnea' named entity 'intestine' named entity 'SARS-CoV-2'

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