About: A perspective on microarrays: current applications, pitfalls, and potential uses

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Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	A perspective on microarrays: current applications, pitfalls, and potential uses
Creator	Betenbaugh, Michael Jaluria, Pratik Konstantopoulos, Konstantinos Shiloach, Joseph Gov, -Yossi@nih
source	Medline; PMC
abstract	With advances in robotics, computational capabilities, and the fabrication of high quality glass slides coinciding with increased genomic information being available on public databases, microarray technology is increasingly being used in laboratories around the world. In fact, fields as varied as: toxicology, evolutionary biology, drug development and production, disease characterization, diagnostics development, cellular physiology and stress responses, and forensics have benefiting from its use. However, for many researchers not familiar with microarrays, current articles and reviews often address neither the fundamental principles behind the technology nor the proper designing of experiments. Although, microarray technology is relatively simple, conceptually, its practice does require careful planning and detailed understanding of the limitations inherently present. Without these considerations, it can be exceedingly difficult to ascertain valuable information from microarray data. Therefore, this text aims to outline key features in microarray technology, paying particular attention to current applications as outlined in recent publications, experimental design, statistical methods, and potential uses. Furthermore, this review is not meant to be comprehensive, but rather substantive; highlighting important concepts and detailing steps necessary to conduct and interpret microarray experiments. Collectively, the information included in this text will highlight the versatility of microarray technology and provide a glimpse of what the future may hold.
has issue date	2007-01-25(xsd:dateTime)
bibo:doi	10.1186/1475-2859-6-4
bibo:pmid	17254338
has license	cc-by
sha1sum (hex)	5c29db6b02088e3b38e416bf32f6a02dbcf9cdf8
schema:url	https://doi.org/10.1186/1475-2859-6-4
resource representing a document's title	A perspective on microarrays: current applications, pitfalls, and potential uses
has PubMed Central identifier	PMC1796898
has PubMed identifier	17254338
schema:publication	Microb Cell Fact
resource representing a document's body	covid:5c29db6b02088e3b38e416bf32f6a02dbcf9cdf8#body_text
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