About: Coinfección vírica en las infecciones respiratorias infantiles

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Coinfección vírica en las infecciones respiratorias infantiles Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Coinfección vírica en las infecciones respiratorias infantiles
Creator	Bonet-Alcaina, M Caballero-Rabasco, M López-Segura, N Martínez-Roig, A Salvadó, M Sánchez-Buenavida, A
Source	Elsevier; PMC
abstract	Resumen Introducción Las técnicas moleculares han permitido un mejor conocimiento de la etiología de las infecciones respiratorias infantiles. El objetivo del estudio fue analizar la coinfección viral y su relación con la gravedad clínica. Métodos Se estudió a pacientes pediátricos hospitalizados con diagnóstico clínico de infección respiratoria durante el periodo comprendido entre 2009 y 2010. Se recogieron datos clínicos, epidemiológicos, duración de la hospitalización, necesidad de oxigenoterapia, coinfección bacteriana y necesidad de ventilación mecánica. Etiología estudiada con técnica PCR múltiple y microarrays de baja densidad para 19 virus. Resultados Un total de 385 pacientes presentaron resultados positivos, 44,94% menores de 12 meses. Los virus más detectados fueron: VRS-B: 139, rhinovirus: 114, VRS-A: 111, influenza A H1N1-2009: 93 y bocavirus: 77. Se detectó coinfección en el 61,81%, un 36,36% con 2 virus, 16,10% con 3 y 9,35% con 4 o más. La coinfección fue superior en 2009 con 69,79 frente 53,88% en 2010. Rhinovirus/VRS-B en 10 ocasiones y VRS-A/VRS-B en 5 fueron las coinfecciones más detectadas. Menor hospitalización a mayor número de virus detectados (p<0,001). Necesitaron oxigenoterapia el 26,75% (en 55,34% se aisló un virus), objetivando a mayor número de virus menor necesidad de oxígeno (p<0,001). Precisaron ventilación mecánica 9 casos, 4 de ellos con coinfección bacteriana y 5 con coinfección vírica (p=0,69). Conclusiones Objetivamos una relación inversamente proporcional entre número de virus detectados en aspirado nasofaríngeo, necesidad de oxigenoterapia y días de hospitalización. Se necesitan más estudios epidemiológicos y mejoría en las técnicas de detección cuantitativa para definir el papel de las coinfecciones víricas en la enfermedad respiratoria y su correlación con la gravedad clínica. Abstract Introduction The introduction of molecular techniques has enabled better understanding of the etiology of respiratory tract infections in children. The objective of the study was to analyze viral coinfection and its relationship to clinical severity. Methods Hospitalized pediatric patients with a clinical diagnosis of respiratory infection were studied during the period between 2009-2010. Clinical and epidemiological data, duration of hospitalization, need for oxygen therapy, bacterial coinfection and need for mechanical ventilation were collected. Etiology was studied by multiplex PCR and low-density microarrays for 19 viruses. Results A total of 385 patients were positive, 44.94% under 12 months. The most frequently detected viruses were RSV-B: 139, rhinovirus: 114, RSV-A: 111, influenza A H1N1-2009: 93 and bocavirus: 77. Coinfection was detected in 61.81%, 36.36% with 2 viruses, 16.10% and 9.35% with 3 to 4 or more. Coinfection was higher in 2009 with 69.79 vs. 53.88% in 2010. Rhinovirus/RSV-B on 10 times and RSV-A/RSV-B on 5 times were the most detected coinfections. Hospitalization decreased with greater number of viruses (P<0,001). Oxygen therapy was required by 26.75% (one virus was detected in 55.34% of cases). A larger number of viruses resulted in less need for oxygen (P<0,001). Ten cases required mechanical ventilation, 4 patients with bacterial coinfection and 5 with viral coinfection (P=0,69). Conclusions An inverse relationship was found between the number of viruses detected in nasopharyngeal aspirate, the need for oxygen therapy and hospitalization days. More epidemiological studies and improved quantitative detection techniques are needed to define the role of viral coinfections in respiratory disease and its correlation with the clinical severity.
has issue date	2015-01-31(xsd:dateTime)
bibo:doi	10.1016/j.arbres.2014.01.018
has license	els-covid
sha1sum (hex)	61ae6ef9c2cd1c9c03744ec3ccbf6e09f9a46f01
schema:url	https://doi.org/10.1016/j.arbres.2014.01.018
resource representing a document's title	Coinfección vírica en las infecciones respiratorias infantiles
has PubMed Central identifier	PMC7127166
schema:publication	Archivos de Bronconeumología
resource representing a document's body	covid:61ae6ef9c2cd1c9c03744ec3ccbf6e09f9a46f01#body_text
is schema:about of	named entity 'MEANS' named entity 'THESE' named entity 'LONG' named entity 'USE' named entity 'analyses' named entity 'publicly funded' named entity 'INFANTILES' named entity 'CENTRE' named entity 'C O' named entity '2015' named entity 'RESOURCE' named entity 'ACTIVE' named entity 'FORM' named entity 'RESEARCH' named entity 'DATABASE' named entity 'REPOSITORIES' named entity 'UNRESTRICTED' named entity 'R C' named entity 'ARCH' named entity 'ORIGINAL' named entity 'FREE' named entity 'RIGHTS' named entity 'FUNDED' named entity '3A5' named entity 'PERMISSIONS' named entity 'COVID-19' named entity 'LAS' named entity 'ORIGINAL SOURCE' named entity 'database' named entity 'original source' named entity '15 años' named entity 'Coinfection' named entity 'Etiology' named entity 'el 1' named entity 'viruses' named entity 'etiology' named entity 'primer' named entity 'oxygen therapy' named entity 'virus' named entity 'nasopharyngeal aspirate' named entity 'coinfections' named entity 'respiratory infection' named entity 'el 1' named entity 'virus' named entity 'virus' named entity 'virus' named entity 'el 16' named entity 'el 9' named entity 'oxygen therapy' named entity 'virus' named entity 'tabla' named entity 'virus' named entity 'pediatric patients' named entity 'virus' named entity 'mechanical ventilation' named entity 'Oxygen therapy' named entity 'los mismos' named entity 'virus' named entity 'la franja' named entity 'respiratory tract infections' named entity 'la tercera' named entity 'virus' named entity 'SEPAR' named entity 'tabla' named entity 'viruses' named entity 'virus' named entity 'Rhinovirus' named entity 'la comunidad' named entity 'coinfections' named entity 'viruses' named entity 'pleural' named entity 'coinfection' named entity 'Streptococcus pneumoniae' named entity 'igual' named entity 'coinfection' named entity 'respiratory disease' named entity 'multiplex PCR' named entity 'Coinfection'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software