About: Acute‐onset smell and taste disorders in the context of COVID‐19: a pilot multicentre polymerase chain reaction based case

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About: Acute‐onset smell and taste disorders in the context of COVID‐19: a pilot multicentre polymerase chain reaction based case–control study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Acute‐onset smell and taste disorders in the context of COVID‐19: a pilot multicentre polymerase chain reaction based case–control study
Creator	Alonso-C Anovas, A Beltr An-Corbellini, A Chico-Garc Ia, J Cort Es-Cuevas, J Fragola-Arnau, C Gal, J Luz, La Madrid, Mart Inez-Poles, J Masjuan, J Monreal, E Natera-Villalba, E Omez-Corral, J Omez-L Opez, A Parra-D Iaz, P Porta-Etessam, J Rodr Iguez-Jorge, F
topic	covid:645bec1add25f5f51b80d6430d2319930fdba7d7#this
source	Medline; PMC
abstract	BACKGROUND AND PURPOSE: Specific respiratory tract infections, including COVID‐19, may cause smell and/or taste disorders (STDs) with increased frequency. The aim was to determine whether new‐onset STDs are more frequent amongst COVID‐19 patients than influenza patients. METHOD: This was a case–control study including hospitalized patients of two tertiary care centres. Consecutive patients positive for COVID‐19 polymerase chain reaction (cases) and patients positive for influenza polymerase chain reaction (historical control sample) were assessed during specific periods, employing a self‐reported STD questionnaire. RESULTS: Seventy‐nine cases and 40 controls were included. No significant differences were found in basal features between the two groups. New‐onset STDs were significantly more frequent amongst cases (31, 39.2%) than in the control group (5, 12.5 %) [adjusted odds ratio 21.4 (2.77–165.4, P = 0.003)]. COVID‐19 patients with new‐onset STDs were significantly younger than COVID‐19 patients without STDs (52.6 ± 17.2 vs. 67.4 ± 15.1, P < 0.001). Amongst COVID‐19 patients who presented STDs, 22 (70.9%) recalled an acute onset and it was an initial manifestation in 11 (35.5%). Twenty‐five (80.6%) presented smell disorders (mostly anosmia, 14, 45.2%) and 28 (90.3%) taste disorders (mostly ageusia, 14, 45.2%). Only four (12.9 %) reported concomitant nasal obstruction. The mean duration of STD was 7.5 ± 3.2 days and 12 patients (40%) manifested complete recovery after 7.4 ± 2.3 days of onset. CONCLUSION: New‐onset STDs were significantly more frequent amongst COVID‐19 patients than influenza patients; they usually had an acute onset and were commonly an initial manifestation. The use of STD assessment in anamnesis as a hint for COVID‐19 and to support individuals’ self‐isolation in the current epidemic context is suggested.
has issue date	2020-05-16(xsd:dateTime)
bibo:doi	10.1111/ene.14273
bibo:pmid	32320508
has license	no-cc
sha1sum (hex)	645bec1add25f5f51b80d6430d2319930fdba7d7
schema:url	https://doi.org/10.1111/ene.14273
resource representing a document's title	Acute‐onset smell and taste disorders in the context of COVID‐19: a pilot multicentre polymerase chain reaction based case–control study
has PubMed Central identifier	PMC7264557
has PubMed identifier	32320508
schema:publication	Eur J Neurol
resource representing a document's body	covid:645bec1add25f5f51b80d6430d2319930fdba7d7#body_text
is http://vocab.deri.ie/void#inDataset of	proxy:http/ns.inria.fr/covid19/645bec1add25f5f51b80d6430d2319930fdba7d7
is schema:about of	named entity 'STDs' named entity 'chain reaction' named entity 'disorders' named entity 'patients' named entity 'patients' named entity 'patients' named entity 'disorders' named entity 'POSITIVE FOR' named entity 'SIGNIFICANT' named entity 'YOUNGER' named entity 'INDIVIDUALS' named entity '7.4' named entity 'SEVENTY-NINE' named entity 'CENTRES' named entity 'MEAN' named entity '2880' named entity '7.5' covid:arg/645bec1add25f5f51b80d6430d2319930fdba7d7 named entity 'control group' named entity 'self-reported' named entity 'patients' named entity 'COVID-19' named entity 'controls' named entity 'STDs' named entity 'COVID-19' named entity 'support' named entity 'features' named entity 'onset' named entity 'respiratory tract infections' named entity 'patients' named entity 'influenza' named entity 'influenza' named entity 'nasal obstruction' named entity 'disorders' named entity 'STDs' named entity 'Results' named entity 'ageusia' named entity 'polymerase chain reaction' named entity 'COVID' named entity 'STDs' named entity 'COVID-19' named entity 'respiratory tract infections' named entity 'COVID' named entity 'influenza' named entity 'STDs' named entity 'COVID' named entity 'anosmia' named entity 'influenza' named entity 'case-control study' named entity 'polymerase chain reaction' named entity 'COVID-19' named entity 'case-control' named entity 'COVID-19' named entity 'STDs' named entity 'drug-induced' named entity 'influenza' named entity 'parainfluenza virus' named entity 'COVID-19' named entity 'polymerase chain reaction' named entity 'dysgeusia' named entity 'COVID-19' named entity 'smoking habit' named entity '2019/2020'

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