About: FIV cross-species transmission: an evolutionary prospective

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About: FIV cross-species transmission: an evolutionary prospective Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	FIV cross-species transmission: an evolutionary prospective
Creator	Pecon-Slattery, Jill Johnson, Warren Antunes, Agostinho O'brien, Stephen Troyer, Jennifer Vandewoude, Sue Franklin, Sam Mcintosh, Carl
source	Elsevier; Medline; PMC
abstract	Feline and primate immunodeficiency viruses (FIVs, SIVs, and HIV) are transmitted via direct contact (e.g. fighting, sexual contact, and mother-offspring transmission). This dynamic likely poses a behavioral barrier to cross-species transmission in the wild. Recently, several host intracellular anti-viral proteins that contribute to species-specificity of primate lentiviruses have been identified revealing adaptive mechanisms that further limit spread of lentiviruses between species. Consistent with these inter-species transmission barriers, phylogenetic evidence supports the prediction that FIV transmission is an exceedingly rare event between free-ranging cat species, though it has occurred occasionally in captive settings. Recently we documented that puma and bobcats in Southern California share an FIV strain, providing an opportunity to evaluate evolution of both viral strains and host intracellular restriction proteins. These studies are facilitated by the availability of the 2X cat genome sequence annotation. In addition, concurrent viral and host genetic analyses have been used to track patterns of migration of the host species and barriers to transmission of the virus within the African lion. These studies illustrate the utility of FIV as a model to discover the variables necessary for establishment and control of lentiviral infections in new species.
has issue date	2008-05-01(xsd:dateTime)
bibo:doi	10.1016/j.vetimm.2008.01.023
bibo:pmid	18299153
has license	green-oa
sha1sum (hex)	646cf3da31ec468a64e1f1710e9573e94586aae5
schema:url	https://doi.org/10.1016/j.vetimm.2008.01.023
resource representing a document's title	FIV cross-species transmission: an evolutionary prospective
has PubMed Central identifier	PMC2442884
has PubMed identifier	18299153
schema:publication	Veterinary Immunology and Immunopathology
resource representing a document's body	covid:646cf3da31ec468a64e1f1710e9573e94586aae5#body_text
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