About: OXA-48 Carbapenemase in Klebsiella pneumoniae Sequence Type 307 in Ecuador

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About: OXA-48 Carbapenemase in Klebsiella pneumoniae Sequence Type 307 in Ecuador Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	OXA-48 Carbapenemase in Klebsiella pneumoniae Sequence Type 307 in Ecuador
Creator	Gestal, Mónica Bodero, Luis Campos, Josefina Castelán-Sánchez, Hugo Dávila-Ramos, Sonia Galas, Marcelo Lazo, Miguel Montero, Lorena Naranjo, Cristina Reyes, Jorge Toapanta, Yadira Villacís, José Wali, Ahmad
source	Medline; PMC
abstract	Antibiotic resistance is on the rise, leading to an increase in morbidity and mortality due to infectious diseases. Klebsiella pneumoniae is a Gram-negative bacterium that causes bronchopneumonia, abscesses, urinary tract infection, osteomyelitis, and a wide variety of infections. The ubiquity of this microorganism confounds with the great increase in antibiotic resistance and have bred great concern worldwide. K. pneumoniae sequence type (ST) 307 is a widespread emerging clone associated with hospital-acquired infections, although sporadic community infections have also been reported. The aim of our study is to describe the first case of Klebsiella pneumoniae (ST) 307 harboring the blaOXA-48-like gene in Ecuador. We characterized a new plasmid that carry OXA-48 and could be the source of future outbreaks. The strain was recovered from a patient with cancer previously admitted in a Ukrainian hospital, suggesting that this mechanism of resistance could be imported. These findings highlight the importance of programs based on active molecular surveillance for the intercontinental spread of multidrug-resistant microorganisms with emergent carbapenemases.
has issue date	2020-03-19(xsd:dateTime)
bibo:doi	10.3390/microorganisms8030435
bibo:pmid	32204571
has license	cc-by
sha1sum (hex)	6f904e32c03752e75e99683cbb9b0c2c2379c464
schema:url	https://doi.org/10.3390/microorganisms8030435
resource representing a document's title	OXA-48 Carbapenemase in Klebsiella pneumoniae Sequence Type 307 in Ecuador
has PubMed Central identifier	PMC7143988
has PubMed identifier	32204571
schema:publication	Microorganisms
resource representing a document's body	covid:6f904e32c03752e75e99683cbb9b0c2c2379c464#body_text
is schema:about of	named entity 'great' named entity 'hospital' named entity 'antibiotic resistance' named entity 'abscesses' named entity 'infectious diseases' named entity 'mechanism' named entity 'Antibiotic resistance' named entity 'surveillance' named entity 'osteomyelitis' named entity 'sporadic' named entity 'aim' named entity 'study' named entity 'highlight' named entity 'Ecuador' named entity 'infectious diseases' named entity 'gene' named entity 'hospital-acquired infections' named entity 'Klebsiella pneumoniae' named entity 'osteomyelitis' named entity 'microorganism' named entity 'OXA' named entity 'Ecuador' named entity 'France' named entity 'palliative treatment' named entity 'Carbapenem' named entity 'plasmid' named entity 'glycogen' named entity 'plasmids' named entity 'mobile elements' named entity 'PCR' named entity 'serine' named entity 'eCIM' named entity 'resistance genes' named entity 'meropenem' named entity 'recA' named entity 'phenotype' named entity 'K. pneumoniae' named entity 'plasmids' named entity 'antibiotic resistance' named entity 'carbapenemases' named entity 'azide' named entity 'hospital settings' named entity 'whole-genome sequencing' named entity 'resistance genes' named entity 'pathogens' named entity 'phenotype' named entity 'Gram-negative bacteria' named entity 'Turkey' named entity 'clones' named entity 'consensus sequence' named entity 'hydrolyzing' named entity 'carbapenemases' named entity 'plasmid' named entity 'globalization' named entity 'carbapenem' named entity 'rpoB' named entity 'KPC' named entity 'Klebsiella pneumoniae' named entity 'Prokaryotic Genomes' named entity 'colorectal cancer' named entity 'piperacillin/tazobactam' named entity 'cephalosporins' named entity 'mCIM' named entity 'Italy' named entity 'global guidelines' named entity 'replicon' named entity 'β-lactam antibiotics' named entity 'plasmids' named entity 'Illumina'

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