About: Lactogenic immunity following vaccination of cattle with bovine coronavirus

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Lactogenic immunity following vaccination of cattle with bovine coronavirus
Creator	Buckley, A Oliver, S Crouch, C Chapman, A Francis, M Hearle, D
source	Elsevier; Medline; PMC
abstract	Abstract In order to investigate the ability of an oil adjuvanted vaccine containing bovine coronavirus antigen to enhance lactogenic immunity in the calf, pregnant cows and heifers were vaccinated and specific virus neutralising antibody levels determined in serum, colostrum and milk. Pre-existing antibody titres (as a result of natural infection) in the serum of these animals were found to be significantly increased as a result of a single shot vaccination carried out between 2 and 12 weeks before calving. This was reflected in a similar increase in the titre and duration of specific antibody in milk and colostrum that was passed on to the calves. The overall response observed was highly dependent on an adequate antigen payload being incorporated within the single dose vaccine. No abnormal local or systemic reactions were observed as a result of vaccination. It is hoped that this approach will lead to the production of a superior commercial vaccine for the protection of neonatal calves against enteric coronavirus infection.
has issue date	2000-09-15(xsd:dateTime)
bibo:doi	10.1016/s0264-410x(00)00177-8
bibo:pmid	10930672
has license	els-covid
sha1sum (hex)	73153c2f1c09eb3479e68b82667961f22f8cb674
schema:url	https://doi.org/10.1016/s0264-410x%2800%2900177-8
resource representing a document's title	Lactogenic immunity following vaccination of cattle with bovine coronavirus
has PubMed Central identifier	PMC7127661
has PubMed identifier	10930672
schema:publication	Vaccine
resource representing a document's body	covid:73153c2f1c09eb3479e68b82667961f22f8cb674#body_text
is schema:about of	named entity 'The' named entity 'antibody' named entity 'virus' named entity 'payload' named entity 'SINGLE' named entity 'NO ABNORMAL' named entity 'ANIMALS' named entity 'INCREASE' named entity 'CALVES' named entity 'NEUTRALISING ANTIBODY' named entity 'ABILITY' named entity 'THESE' named entity 'CARRIED' named entity 'ADEQUATE' named entity 'CONTAINING' named entity 'PROTECTION' named entity 'VACCINATED' named entity 'COLOSTRUM' named entity 'PREGNANT' named entity 'VIRUS' named entity 'SERUM' covid:arg/73153c2f1c09eb3479e68b82667961f22f8cb674 named entity 'CATTLE' named entity 'IMMUNITY' named entity 'REACTIONS' named entity 'VACCINE' named entity 'ORDER' named entity 'AEC' named entity 'ANTIBODY TITRES' named entity 'SIMILAR' named entity 'IMMUNITY' named entity 'FOUND' named entity 'ENTERIC CORONAVIRUS' named entity 'PASSED' named entity 'BOVINE CORONAVIRUS' named entity 'VACCINATION' named entity 'ANTIGEN' named entity 'SUPERIOR' named entity 'BEING' named entity 'TITRE' named entity 'LOCAL' named entity 'CORONAVIRUS INFECTION' named entity 'MILK' named entity 'OIL' named entity 'COWS' named entity '12 WEEKS' named entity 'FOLLOWING' named entity 'ENHANCE' named entity 'COMMERCIAL' named entity 'APPROACH' named entity 'AS A RESULT OF' named entity 'DOSE' named entity 'ADJUVANTED' named entity 'CALVING' named entity 'OVERALL RESPONSE' named entity 'INCREASED' named entity 'LEAD' named entity 'THE CALF' named entity 'HIGHLY' named entity 'DETERMINED' named entity 'PRE-EXISTING' named entity 'RESULT' named entity 'ANTIBODY' named entity 'DEPENDENT' named entity 'NEONATAL' named entity 'PRODUCTION' named entity 'OBSERVED' named entity 'VACCINATION' named entity 'LEVELS' named entity 'SYSTEMIC' named entity 'BOVINE CORONAVIRUS ANTIGEN' named entity 'TO INVESTIGATE' named entity 'DURATION' named entity 'SHOT' named entity 'NATURAL INFECTION' named entity 'heifers'

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