About: Prevalence of enteric viruses among hospital patients with AIDS in Kinshasa, Zaire

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Prevalence of enteric viruses among hospital patients with AIDS in Kinshasa, Zaire
Creator	Atido, Uvoya Glass, Roger Kapita, Bila Mabaluku, Mwamba Ngoy, Benjamin Perriens, Jos Grohmann, Gary Keusch, Gerald Thea, Donald
Source	Elsevier; Medline; PMC
abstract	Abstract Diarrhoea is the most common manifestation of acquired immunodeficiency syndrome (AIDS) in Africa. Numerous parasitic or bacterial agents have been implicated, but a pathogen-specific aetiology has not been found. Enteric viruses (i.e., rotavirus, small round structured viruses, coronavirus, and adenovirus) were detected by enzyme-linked immunosorbent assay or electron microscopy in faecal specimens of 17% of 198 consecutive adult admissions to a general medical ward of an urban hospital in Kinshasa, Zaire. Overall, 57% of patients were seropositive for infection with human immunodeficiency virus (HIV) 1; of these, 50% were classified as World Health Organization Aids stage IV. The prevalence of enteric viruses in stool specimens did not differ significantly between patients with and without HIV infection, and was not associated with acute or chronic diarrhoea, or constitutional symptoms. However, a trend (P = 0·14) towards greater frequency of virus in stools from patients in the lower 3 quintiles of the CD4/CD8 T cell ratio was seen. This trend approached statistical significance (P = 0·07) with stratification by HIV infection. Although we found no evidence in this population to support a major pathogenic role for these viruses alone in the enteropathy of AIDS, increased viral shedding was weakly associated with immunodeficiency.
has issue date	1993-06-30(xsd:dateTime)
bibo:doi	10.1016/0035-9203(93)90119-b
bibo:pmid	8236386
has license	els-covid
sha1sum (hex)	73172d9a1ad58275800cf7bf7232bf0f988a7366
schema:url	https://doi.org/10.1016/0035-9203%2893%2990119-b
resource representing a document's title	Prevalence of enteric viruses among hospital patients with AIDS in Kinshasa, Zaire
has PubMed Central identifier	PMC7107222
has PubMed identifier	8236386
schema:publication	Transactions of the Royal Society of Tropical Medicine and Hygiene
resource representing a document's body	covid:73172d9a1ad58275800cf7bf7232bf0f988a7366#body_text
is schema:about of	named entity 'AIDS' named entity 'medical' named entity 'AIDS' named entity 'ratio' named entity 'hospital' named entity 'enteric viruses' named entity 'BACTERIAL' named entity 'DID' named entity 'THESE' named entity 'STOOL' named entity 'PARASITIC' named entity 'ASSOCIATED WITH' named entity 'CLASSIFIED' named entity 'INFECTION' named entity 'ELECTRON MICROSCOPY' named entity 'STATISTICAL SIGNIFICANCE' named entity 'STOOLS' named entity 'TO SUPPORT' named entity 'HAVE' named entity '28I' named entity 'EVIDENCE' named entity 'OVERALL' named entity 'POPULATION' named entity 'ADENOVIRUS' named entity 'ROUND' named entity 'ROTAVIRUS' named entity 'ENTEROPATHY' named entity 'ENTERIC' named entity 'GENERAL MEDICAL WARD' named entity 'AFRICA' named entity 'AIDS' named entity 'VIRUSES' named entity 'PREVALENCE' named entity 'ENTERIC' named entity 'T CELL' named entity 'BUT' named entity 'CONSECUTIVE' named entity 'FOUND' named entity 'MANIFESTATION OF' named entity 'ADMISSIONS' named entity 'GREATER' named entity 'ADULT' named entity 'ZAIRE' named entity 'PATHOGEN' named entity 'STRUCTURED' named entity 'PATIENTS' named entity 'ACQUIRED IMMUNODEFICIENCY SYNDROME' named entity 'STAGE IV' named entity 'VIRUS' named entity 'LOWER' named entity 'HUMAN IMMUNODEFICIENCY VIRUS' named entity 'FAECAL' named entity 'SPECIFIC' named entity 'NUMEROUS' named entity 'AIDS' named entity 'PATHOGENIC' named entity 'A MAJOR' named entity 'HOSPITAL PATIENTS' named entity 'VIRAL SHEDDING' named entity 'DIARRHOEA' named entity 'URBAN HOSPITAL' named entity 'SEEN' named entity 'VIRUSES' named entity 'DETECTED' named entity 'ROLE' named entity 'ZAIRE' named entity 'RATIO' named entity 'SEROPOSITIVE' named entity '28P' named entity 'CONSTITUTIONAL SYMPTOMS' named entity 'WORLD HEALTH ORGANIZATION' named entity 'STRATIFICATION' named entity 'FREQUENCY'

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