About: Risk Factors for Acute Kidney Injury and In-Hospital Mortality in Patients Receiving Extracorporeal Membrane Oxygenation

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About: Risk Factors for Acute Kidney Injury and In-Hospital Mortality in Patients Receiving Extracorporeal Membrane Oxygenation Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Risk Factors for Acute Kidney Injury and In-Hospital Mortality in Patients Receiving Extracorporeal Membrane Oxygenation
Creator	Lee, Hajeong Kim, Sejoong Ahn, Shin Lee, Sung Chin, Ho Na, Ki Yu, Mi-Yeon
Source	Medline; PMC
abstract	BACKGROUND AND OBJECTIVES: Although acute kidney injury (AKI) is the most frequent complication in patients receiving extracorporeal membrane oxygenation (ECMO), few studies have been conducted on the risk factors of AKI. We performed this study to identify the risk factors of AKI associated with in-hospital mortality. METHODS: Data from 322 adult patients receiving ECMO were analyzed. AKI and its stages were defined according to Kidney Disease Improving Global Outcomes (KDIGO) classifications. Variables within 24 h before ECMO insertion were collected and analyzed for the associations with AKI and in-hospital mortality. RESULTS: Stage 3 AKI was associated with in-hospital mortality, with a hazard ratio (HR) (95% CI) of 2.690 (1.472–4.915) compared to non-AKI (p = 0.001). The simplified acute physiology score 2 (SAPS2) and serum sodium level were also associated with in-hospital mortality, with HRs of 1.02 (1.004–1.035) per 1 score increase (p = 0.01) and 1.042 (1.014–1.070) per 1 mmol/L increase (p = 0.003). The initial pump speed of ECMO was significantly related to in-hospital mortality with a HR of 1.333 (1.020–1.742) per 1,000 rpm increase (p = 0.04). The pump speed was also associated with AKI (p = 0.02) and stage 3 AKI (p = 0.03) with ORs (95% CI) of 2.018 (1.129–3.609) and 1.576 (1.058–2.348), respectively. We also found that the red cell distribution width (RDW) above 14.1% was significantly related to stage 3 AKI. CONCLUSION: The initial pump speed of ECMO was a significant risk factor of in-hospital mortality and AKI in patients receiving ECMO. The RDW was a risk factor of stage 3 AKI.
has issue date	2015-10-15(xsd:dateTime)
bibo:doi	10.1371/journal.pone.0140674
bibo:pmid	26469793
has license	cc-by
sha1sum (hex)	732dff5e34c82bab1a77fe07eeff62b1a0e44fa7
schema:url	https://doi.org/10.1371/journal.pone.0140674
resource representing a document's title	Risk Factors for Acute Kidney Injury and In-Hospital Mortality in Patients Receiving Extracorporeal Membrane Oxygenation
has PubMed Central identifier	PMC4607159
has PubMed identifier	26469793
schema:publication	PLoS One
resource representing a document's body	covid:732dff5e34c82bab1a77fe07eeff62b1a0e44fa7#body_text
is schema:about of	named entity 'PATIENTS' named entity 'ACUTE KIDNEY INJURY' named entity 'EXTRACORPOREAL MEMBRANE OXYGENATION' named entity 'FREQUENT' named entity 'PATIENTS' named entity 'RISK FACTORS' named entity 'TO IDENTIFY' named entity 'AKI' named entity 'COMPLICATION' named entity 'EXTRACORPOREAL MEMBRANE OXYGENATION' named entity 'HAVE' named entity 'RISK FACTORS' named entity 'RECEIVING' named entity 'PERFORMED' named entity 'STUDY' named entity 'RECEIVING' named entity 'ASSOCIATED WITH' named entity 'ACUTE KIDNEY INJURY' named entity 'HOSPITAL MORTALITY' named entity 'STUDIES' named entity 'IN-HOSPITAL MORTALITY' covid:arg/732dff5e34c82bab1a77fe07eeff62b1a0e44fa7 named entity 'AKI' named entity 'extracorporeal membrane oxygenation' named entity 'risk factors' named entity 'Hirrlingen' named entity 'ECMO' named entity 'hemolysis' named entity 'ECMO' named entity 'ECMO' named entity 'centrifugal pump' named entity 'urine' named entity 'ECMO' named entity 'critical illness' named entity 'biomarker' named entity 'hemolysis' named entity 'decannulation' named entity 'standard deviation' named entity 'risk factor' named entity 'cardiopulmonary resuscitation' named entity 'ECMO' named entity 'ECMO' named entity 'μmol/L' named entity 'regression analysis' named entity 'RDW' named entity 'ECMO' named entity 'BUN' named entity 'Maquet' named entity 'hemoglobin' named entity 'hemoglobin' named entity 'ECMO' named entity 'RDW' named entity 'peak inspiratory pressure' named entity 'membrane oxygenator' named entity 'ECMO' named entity 'rheumatoid arthritis' named entity 'statistically significant' named entity 'stage 3' named entity '1.02' named entity '0.01' named entity 'log-rank test' named entity 'inflammation' named entity 'Alzheimer's disease' named entity 'Japan' named entity 'Physiology' named entity 'intra-aortic balloon pump' named entity 'ECMO' named entity 'IABP' named entity 'white blood cells' named entity 'risk factor' named entity 'CRP' named entity 'ECMO' named entity 'risk factor' named entity 'RDW' named entity 'ECMO'

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