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About:
Improved COVID-19 Serology Test Performance by Integrating Multiple Lateral Flow Assays using Machine Learning
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Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
title
Improved COVID-19 Serology Test Performance by Integrating Multiple Lateral Flow Assays using Machine Learning
Creator
Song, Yun
Marson, Alexander
Mowery, Cody
Ye, Chun
source
MedRxiv
abstract
Mitigating transmission of SARS-CoV-2 has been complicated by the inaccessibility and, in some cases, inadequacy of testing options to detect present or past infection. Immunochromatographic lateral flow assays (LFAs) are a cheap and scalable modality for tracking viral transmission by testing for serological immunity, though systematic evaluations have revealed the low performance of some SARS-CoV-2 LFAs. Here, we re-analyzed existing data to present a proof-of-principle machine learning framework that may be used to inform the pairing of LFAs to achieve superior classification performance while enabling tunable False Positive Rates optimized for the estimated seroprevalence of the population being tested.
has issue date
2020-07-16
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xsd:dateTime
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bibo:doi
10.1101/2020.07.15.20154773
has license
medrxiv
sha1sum (hex)
774f2c22356e3d2a1d0f164b436fd849c786eb73
schema:url
https://doi.org/10.1101/2020.07.15.20154773
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Improved COVID-19 Serology Test Performance by Integrating Multiple Lateral Flow Assays using Machine Learning
resource representing a document's body
covid:774f2c22356e3d2a1d0f164b436fd849c786eb73#body_text
is
schema:about
of
named entity 'immunity'
named entity 'cases'
named entity 'BEING'
named entity 'SEROPREVALENCE'
named entity 'USED'
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