About: Evidence for Cross-Protection Against Subsequent Febrile Respiratory Illness Episodes From Prior Infections by Different Viruses Among Singapore Military Recruits 2009

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About: Evidence for Cross-Protection Against Subsequent Febrile Respiratory Illness Episodes From Prior Infections by Different Viruses Among Singapore Military Recruits 2009–2014 Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Evidence for Cross-Protection Against Subsequent Febrile Respiratory Illness Episodes From Prior Infections by Different Viruses Among Singapore Military Recruits 2009–2014
Creator	Lee, Vernon Tan, Boon-Huan Pang, Junxiong Zhao, Xiahong Chng, Jeremiah Sun, Yinxiaohe Tambyah, Paul Cook, Alex Loh, Jin Ng, Sock, Hoon Chen, I-Cheng Chuah, Cheryl Gao, Christine Goh, Ee Han, Qiu Koh, Wee-Hong
source	Medline; PMC
abstract	BACKGROUND: Few studies have evaluated the relative cross-protection conferred by infection with different groups of viruses through studies of sequential infections in humans. We investigated the presence of short-lived relative cross-protection conferred by specific prior viral infections against subsequent febrile respiratory illness (FRI). METHODS: Men enlisted in basic military training between December 2009 and December 2014 were recruited, with the first FRI as the study entry point. ResPlex II assays and real-time polymerase chain reaction assays were used to detect viral pathogens in nasal wash samples, and survival analyses were performed to determine whether infection with particular viruses conferred short-lived relative cross-protection against FRI. RESULTS: Prior infection with adenovirus (hazard ratio [HR], 0.24; 95% confidence interval [CI], .14–.44) or influenza virus (HR, 0.52; 95% CI, .38–.73) conferred relative protection against subsequent FRI episode. Results were statistically significant even after adjustment for the interval between enlistment and FRI (P < .001). Adenovirus-positive participants with FRI episodes tended to be protected against subsequent infection with adenovirus, coronavirus, enterovirus/rhinovirus, and influenza virus (P = .062–.093), while men with influenza virus–positive FRI episodes tended be protected against subsequent infection with adenovirus (P = .044) and influenza virus (P = .081). CONCLUSION: Prior adenovirus or influenza virus infection conferred cross-protection against subsequent FRI episodes relative to prior infection due to other circulating viruses.
has issue date	2019-06-15(xsd:dateTime)
bibo:doi	10.1093/infdis/jiz046
bibo:pmid	30722024
has license	cc-by-nc-nd
sha1sum (hex)	81cfdc6601a05ba9db405a714d3372ea328a2186
schema:url	https://doi.org/10.1093/infdis/jiz046
resource representing a document's title	Evidence for Cross-Protection Against Subsequent Febrile Respiratory Illness Episodes From Prior Infections by Different Viruses Among Singapore Military Recruits 2009–2014
has PubMed Central identifier	PMC6534195
has PubMed identifier	30722024
schema:publication	J Infect Dis
resource representing a document's body	covid:81cfdc6601a05ba9db405a714d3372ea328a2186#body_text
is schema:about of	named entity 'VIRUSES' named entity 'FEBRILE' named entity 'PROTECTION' named entity 'VIRAL INFECTIONS' named entity 'HUMANS' named entity 'RELATIVE' named entity 'INFECTIONS' named entity 'STUDIES' named entity 'respiratory illness' named entity 'viral infections' named entity 'Illness' named entity 'Viruses' named entity 'SUBSEQUENT' named entity 'DIFFERENT' named entity 'DIFFERENT' named entity 'JOURNAL ' covid:arg/81cfdc6601a05ba9db405a714d3372ea328a2186 named entity 'INVESTIGATED' named entity 'GROUPS' named entity 'EPISODES' named entity 'SUBSEQUENT' named entity 'SINGAPORE' named entity 'PROTECTION' named entity 'PRIOR' named entity 'INFECTIOUS DISEASES' named entity 'MILITARY' named entity 'HAVE' named entity 'VIRUSES' named entity 'SHORT' named entity 'SPECIFIC' named entity 'EVALUATED' named entity 'EVIDENCE FOR' named entity 'RESPIRATORY ILLNESS' named entity 'CROSS' named entity 'FEBRILE' named entity 'INFECTIONS' named entity 'CROSS' named entity 'INFECTION' named entity 'PRESENCE OF' named entity 'SEQUENTIAL' named entity 'BACKGROUND' named entity 'RESPIRATORY ILLNESS' named entity 'PRIOR' named entity 'infections' named entity 'subsequent' named entity 'Singapore' named entity 'FRI' named entity 'febrile' named entity 'infection' named entity 'Febrile' named entity 'Viruses' named entity 'influenza' named entity 'etiological' named entity 'influenza' named entity 'viruses' named entity 'febrile illness' named entity 'virus' named entity 'viruses' named entity 'incidence rates' named entity 'AdV' named entity 'cohort study' named entity 'incidence rates' named entity 'animal models' named entity 'viruses' named entity 'data set'

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