About: First Isolation and Rapid Identification of Newcastle Disease Virus from Aborted Fetus of Dromedary Camel Using Next-Generation Sequencing

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About: First Isolation and Rapid Identification of Newcastle Disease Virus from Aborted Fetus of Dromedary Camel Using Next-Generation Sequencing Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	First Isolation and Rapid Identification of Newcastle Disease Virus from Aborted Fetus of Dromedary Camel Using Next-Generation Sequencing
Creator	Chan, Kwok-Hung Joseph, Sunitha Wernery, Ulrich Fung, Joshua Kinne, Joerg Lee, Hwei Yeong, Kai Chiu, Patrick Kar, Susanna Korah, Shyna Lau, Pui Lee, Jade Teng, Woo, Yat
source	Medline; PMC
abstract	Newcastle disease virus (NDV) causes morbidities and mortalities in wild and domestic birds globally. For humans, exposure to infected birds can cause conjunctivitis and influenza-like symptoms. NDV infections in mammals are rarely reported. In this study, using next-generation sequencing, an NDV was identified and isolated from Vero cells inoculated with the nasal swab of an aborted dromedary fetus in Dubai, during the time when an NDV outbreak occurred in a pigeon farm located in close proximity to the dairy camel farm where the mother of the aborted dromedary fetus resided, and there were a lot of pigeons in the camel farm. Genome analysis revealed that the structurally and functionally important features of other NDVs were also present in this dromedary NDV genome. Phylogenetic analysis based on the nucleotide sequences of fusion protein (F), hemagglutinin-neuraminidase protein (HN) and complete polyprotein showed that the virus belonged to sub-genotype VIg of class II NDV and is most closely related to pigeon NDVs in Egypt in the same year. The present study is the first that demonstrated isolation of NDV in dromedaries. Further study is warranted to investigate the relationship between NDV infection and abortion.
has issue date	2019-09-01(xsd:dateTime)
bibo:doi	10.3390/v11090810
bibo:pmid	31480604
has license	cc-by
sha1sum (hex)	821adc5f0139622999cf4d6a2f622b51b15a07bc
schema:url	https://doi.org/10.3390/v11090810
resource representing a document's title	First Isolation and Rapid Identification of Newcastle Disease Virus from Aborted Fetus of Dromedary Camel Using Next-Generation Sequencing
has PubMed Central identifier	PMC6783818
has PubMed identifier	31480604
schema:publication	Viruses
resource representing a document's body	covid:821adc5f0139622999cf4d6a2f622b51b15a07bc#body_text
is schema:about of	named entity 'FEATURES' named entity 'MOTHER' named entity 'INFECTIONS' named entity 'RELATIONSHIP' named entity 'GENOME ANALYSIS' named entity 'DUBAI' named entity 'ISOLATED' named entity 'YEAR' named entity 'INFECTION' named entity 'DOMESTIC' named entity 'NEXT-GENERATION SEQUENCING' named entity 'HEMAGGLUTININ-NEURAMINIDASE' named entity 'NUCLEOTIDE SEQUENCES' named entity 'BIRDS' named entity 'PRESENT' named entity 'A LOT OF' named entity 'MORTALITIES' named entity 'OCCURRED' named entity 'CLASS II' named entity 'HUMANS' named entity 'STUDY' named entity 'MAMMALS' named entity 'ABORTED FETUS' named entity 'time' named entity 'dairy' named entity 'morbidities' named entity 'protein' named entity 'mammals' named entity 'Fetus' named entity 'Isolation' named entity 'Identification' named entity 'NEWCASTLE DISEASE VIRUS' named entity 'IDENTIFICATION' named entity 'PROXIMITY' named entity 'FARM' named entity 'EGYPT' named entity 'PROTEIN ' named entity 'WHERE' named entity 'COMPLETE' named entity 'MORBIDITIES' named entity 'PIGEON' named entity 'INFLUENZA-LIKE SYMPTOMS' named entity 'ABORTED' named entity 'REVEALED' named entity 'CAUSES' named entity 'REPORTED' named entity 'USING' named entity 'DROMEDARY CAMEL' named entity 'RAPID' named entity 'USING' named entity 'NEXT-GENERATION SEQUENCING' named entity 'ISOLATION' named entity 'FETUS' named entity 'POLYPROTEIN' named entity 'ABORTION' named entity 'SUB-' named entity 'TO INVESTIGATE' named entity 'PHYLOGENETIC ANALYSIS' named entity 'RELATED' named entity 'GENOTYPE' named entity 'NASAL SWAB' named entity 'CAUSE' named entity 'IMPORTANT' named entity 'VERO CELLS' named entity 'CAMEL' named entity 'OUTBREAK' named entity 'LOCATED IN' named entity 'ISOLATION'

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