About: Ficus septica plant extracts for treating Dengue virus in vitro

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Ficus septica plant extracts for treating Dengue virus in vitro
Creator	Chang, Tsung-Hsien Lin, You-Sheng Tsai, Wei-Lun Weng, Jing-Ru Chen, Jih-Jung Huang, Mei-Shu Huang, Nan-Chieh Hung, Wan-Ting Lai, Feng-Yi Lin, Wei-Yu
source	Medline; PMC
abstract	Dengue virus types 1-4 (DENV-1-4) are positive-strand RNA viruses with an envelope that belongs to the Flaviviridae. DENV infection threatens human health worldwide. However, other than supportive treatments, no specific therapy is available for the infection. In order to discover novel medicine against DENV, we tested 59 crude extracts, without cytotoxicity, from 23 plants in vitro; immunofluorescence assay revealed that the methanol extracts of fruit, heartwood, leaves and stem from Ficus septica Burm. f. had a promising anti-DENV-1 and DENV-2 effect. However, infection with the non-envelope picornavirus, Aichi virus, was not inhibited by treatment with F. septica extracts. F. septica may be a candidate antiviral drug against an enveloped virus such as DENV.
has issue date	2017-06-08(xsd:dateTime)
bibo:doi	10.7717/peerj.3448
bibo:pmid	28607841
has license	cc-by
sha1sum (hex)	83d150bdc1e4fdc24ecc74e0fd09d5fd7791cc65
schema:url	https://doi.org/10.7717/peerj.3448
resource representing a document's title	Ficus septica plant extracts for treating Dengue virus in vitro
has PubMed Central identifier	PMC5466810
has PubMed identifier	28607841
schema:publication	PeerJ
resource representing a document's body	covid:83d150bdc1e4fdc24ecc74e0fd09d5fd7791cc65#body_text
is schema:about of	named entity 'FRUIT' named entity 'ORDER' named entity 'IN VITRO' named entity 'NON-' named entity 'TREATMENTS' named entity 'PICORNAVIRUS' named entity 'SPECIFIC' named entity 'MAY BE A' named entity 'NOVEL' named entity 'AICHI VIRUS' named entity 'THERAPY' named entity 'STRAND' named entity 'Dengue virus' named entity 'PLANT EXTRACTS' named entity 'DISTRIBUTED' named entity 'RNA VIRUSES' named entity 'ENVELOPE' named entity 'PLANTS' named entity 'HEARTWOOD' named entity 'OTHER THAN' named entity 'LEAVES' named entity 'IMMUNOFLUORESCENCE ASSAY' named entity 'STEM' named entity 'HUMAN HEALTH' named entity 'TREATMENT' named entity 'FLAVIVIRIDAE' named entity 'SUPPORTIVE' named entity 'AVAILABLE' named entity 'DENGUE VIRUS' named entity 'FICUS SEPTICA' covid:arg/83d150bdc1e4fdc24ecc74e0fd09d5fd7791cc65 named entity 'TREATING' named entity 'IN VITRO' named entity 'DENV-1' named entity 'VIRUS TYPES' named entity 'CANDIDATE' named entity 'EXTRACTS' named entity 'DENV-2' named entity 'INHIBITED' named entity 'INFECTION' named entity 'BURM' named entity 'METHANOL' named entity 'FICUS SEPTICA' named entity 'TESTED' named entity 'CYTOTOXICITY' named entity 'CREATIVE COMMONS' named entity 'DENGUE VIRUS' named entity 'EFFECT' named entity 'ANTIVIRAL DRUG' named entity 'ENVELOPED VIRUS' named entity 'DISCOVER' named entity 'WORLDWIDE' named entity 'POSITIVE' named entity 'MEDICINE' named entity 'REVEALED' named entity 'However' named entity 'promising' named entity 'discover' named entity 'Flaviviridae' named entity 'RNA' named entity 'Distributed' named entity 'infection' named entity 'infection' named entity 'RNA viruses' named entity 'virus' named entity 'Flaviviridae' named entity 'Aichi' named entity 'human health' named entity 'antiviral drug' named entity 'fruit' named entity 'DENV' named entity 'methanol'

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