About: Tracheostomy, ventilatory wean, and decannulation in COVID-19 patients

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Tracheostomy, ventilatory wean, and decannulation in COVID-19 patients
Creator	Wyncoll, Duncan Ahmad, Imran Arora, · Surda, Pavol Archer, Sally Dinham, Alison Simo, Ricard Tornari, Chrysostomos Amin, Nikul Harding, Rachel Ranford, David Tricklebank, Stephen Arunjit Takhar, ·
Source	Medline; PMC
abstract	PURPOSE: COVID-19 patients requiring mechanical ventilation can overwhelm existing bed capacity. We aimed to better understand the factors that influence the trajectory of tracheostomy care in this population to facilitate capacity planning and improve outcomes. METHODS: We conducted an observational cohort study of patients in a high-volume centre in the worst-affected region of the UK including all patients that underwent tracheostomy for COVID-19 pneumonitis ventilatory wean from 1st March 2020 to 10th May 2020. The primary outcome was time from insertion to decannulation. The analysis utilised Cox regression to account for patients that are still progressing through their tracheostomy pathway. RESULTS: At the point of analysis, a median 21 days (IQR 15–28) post-tracheostomy and 39 days (IQR 32–45) post-intubation, 35/69 (57.4%) patients had been decannulated a median of 17 days (IQR 12-20.5) post-insertion. The overall median age was 55 (IQR 48–61) with a male-to-female ratio of 2:1. In Cox regression analysis, FiO(2) at tracheostomy ≥ 0.4 (HR 1.80; 95% CI 0.89–3.60; p = 0.048) and last pre-tracheostomy peak cough flow (HR 2.27; 95% CI 1.78–4.45; p = 0.001) were independent variables associated with prolonged time to decannulation. CONCLUSION: Higher FiO(2) at tracheostomy and higher pre-tracheostomy peak cough flow are associated with increased delay in COVID-19 tracheostomy patient decannulation. These finding comprise the most comprehensive report of COVID-19 tracheostomy decannulation to date and will assist service planning for future peaks of this pandemic.
has issue date	2020-08-01(xsd:dateTime)
bibo:doi	10.1007/s00405-020-06187-1
bibo:pmid	32740720
has license	no-cc
sha1sum (hex)	8615ff2c88b2bc67c80531c581f756ca17583f22
schema:url	https://doi.org/10.1007/s00405-020-06187-1
resource representing a document's title	Tracheostomy, ventilatory wean, and decannulation in COVID-19 patients
has PubMed Central identifier	PMC7395208
has PubMed identifier	32740720
schema:publication	Eur Arch Otorhinolaryngol
resource representing a document's body	covid:8615ff2c88b2bc67c80531c581f756ca17583f22#body_text
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