About: Characterization and pathogenicity of a novel mammalian orthoreovirus from wild short-nosed fruit bats

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About: Characterization and pathogenicity of a novel mammalian orthoreovirus from wild short-nosed fruit bats Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Characterization and pathogenicity of a novel mammalian orthoreovirus from wild short-nosed fruit bats
Creator	Liu, Shengwang Shao, Yuhao Hu, Xiaoliang Qu, Liandong Li, Zhijie Tian, Jin Liu, Chunguo Zhang, Xiaozhan Guo, Dongchun Liu, Dafei Ran, Xuhua
source	Elsevier; Medline; PMC
abstract	Mammalian orthoreoviruses (MRVs) have a wide range of geographic distribution and have been isolated from humans and various animals. This study describes the isolation, molecular characterization and analysis of pathogenicity of MRV variant B/03 from wild short-nosed fruit bats. Negative stain electron microscopy illustrated that the B/03 strain is a non-enveloped icosahedral virus with a diameter of 70 nm. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) migration patterns showed that the B/03 viral genome contains 10 segments in a 3:3:4 arrangement. The isolate belongs to MRV serotype 1 based on S1 gene nucleotide sequence data. BALB/c mice experimentally infected with B/03 virus by intranasal inoculation developed severe respiratory distress with tissue damage and inflammation. Lastly, B/03 virus has an increased transmission risk between bats and humans or animals.
has issue date	2016-05-31(xsd:dateTime)
bibo:doi	10.1016/j.meegid.2016.05.039
bibo:pmid	27259366
has license	no-cc
sha1sum (hex)	8a569c06cd75f733386979cbd3e15c83a8816570
schema:url	https://doi.org/10.1016/j.meegid.2016.05.039
resource representing a document's title	Characterization and pathogenicity of a novel mammalian orthoreovirus from wild short-nosed fruit bats
has PubMed Central identifier	PMC7106163
has PubMed identifier	27259366
schema:publication	Infect Genet Evol
resource representing a document's body	covid:8a569c06cd75f733386979cbd3e15c83a8816570#body_text
is schema:about of	named entity 'WILD' named entity 'risk' named entity 'virus' named entity 'orthoreoviruses' named entity 'Characterization' named entity 'VARIOUS' named entity 'RESPIRATORY DISTRESS' named entity 'NEGATIVE STAIN ELECTRON MICROSCOPY' named entity 'RANGE' named entity 'HAVE' named entity 'IS A' named entity 'NON-' named entity 'CHARACTERIZATION' named entity 'INCREASED' named entity 'ARRANGEMENT' named entity 'MOLECULAR' named entity 'PAGE' named entity 'BASED' named entity 'MICE' named entity 'BALB' named entity 'SEGMENTS' named entity 'ISOLATION' named entity 'ISOLATE' named entity 'NOSED' named entity 'MAMMALIAN ORTHOREOVIRUS' named entity 'PATHOGENICITY' named entity 'FRUIT BATS' named entity 'CHARACTERIZATION' named entity 'STUDY' named entity '3A4' named entity 'SODIUM DODECYL SULFATE-POLYACRYLAMIDE GEL ELECTROPHORESIS' named entity 'TRANSMISSION' named entity 'ANALYSIS' named entity 'WIDE' named entity 'NOVEL' named entity 'NOSED' named entity 'SHORT' named entity 'FRUIT BATS' named entity 'PATTERNS' named entity 'DIAMETER' named entity 'PATHOGENICITY' named entity 'NUCLEOTIDE SEQUENCE' named entity 'SEQUENCE DATA' named entity 'MIGRATION' named entity 'INFECTED' named entity 'HUMANS' named entity 'VIRAL GENOME' named entity 'ANIMALS' named entity 'S1 GENE' named entity 'CONTAINS' named entity 'SEROTYPE' named entity 'ISOLATED' named entity 'MAMMALIAN ORTHOREOVIRUSES' named entity 'BATS' named entity 'SEVERE' named entity 'GEOGRAPHIC DISTRIBUTION' named entity 'RISK' named entity 'WILD' named entity 'INFLAMMATION' named entity 'INTRANASAL INOCULATION' named entity 'SHORT' named entity 'STRAIN' named entity 'VIRUS' named entity 'VARIANT' named entity 'TISSUE DAMAGE' covid:arg/8a569c06cd75f733386979cbd3e15c83a8816570 named entity 'strain' named entity 'fruit bats' named entity 'experimentally' named entity 'dodecyl' named entity 'intranasal'

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