About: Colostrum oropharyngeal immunotherapy for very low birth weight preterm infants: protocol of an intervention study

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Colostrum oropharyngeal immunotherapy for very low birth weight preterm infants: protocol of an intervention study Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	Colostrum oropharyngeal immunotherapy for very low birth weight preterm infants: protocol of an intervention study
Creator	Oliveira Vieira, Graciete Santos Passos Costa, Jéssica Amaral, Cardoso Cerqueira, Ellayne Da, Camilla De Oliveira Vieira, Tatiana De, Michelle Martins, Cruz Ramos, Santana Seixas Da Cruz, Simone Viana, Mara
Source	PMC
abstract	BACKGROUND: The oropharyngeal colostrum administration protocol to treat premature newborns is a possible and plausible strategy in neonatal health services, since the immunoprotective components of colostrum can be absorbed by the lymphoid tissues of the oropharynx. In this context, this study aims to describe the implementation of oropharyngeal colostrum immunotherapy in very low birth weight preterm newborns in a neonatal unit, as well as to test an algorithm in a public hospital. METHODS: The protocol is applied in a non-randomized, superiority clinical trial with historical control. In the treatment group, 0.2 mL of raw colostrum is dripped into the right and left oropharyngeal mucosa, totaling 8 administrations every 24 h until the 7th complete day of life interruptedly. The control group consists of very low birth weight preterm newborns born in the same hospital in previous years (historical control). The clinical progression of 60 newborns until hospital discharge is recorded on standardized forms. A total of 350 participants are estimated to complete the survey in 4 years. The occurrence of continuous outcomes between the groups are compared through the paired t-test or Wilcoxon’s two-sample test. The chi-square test or Fisher’s exact test, and survival analysis are used for binary outcomes. The nutritional status is assessed through Intergrowth-21st growth curves for preterm newborns. DISCUSSION: The flows of the protocol’s actions is sorted by an algorithm, compatible with the Brazilian reality of a public hospital. This measure facilitates and systematizes clinical care, organizes the team’s work process, speeds up the intervention steps, standardizes decision-making and unifies the quality of care, besides showing the feasibility of oropharyngeal colostrum immunotherapy. TRIAL REGISTRATION: ReBEC, U1111–1222-0598, Registered 09 October 2018, http://www.ensaiosclinicos.gov.br/rg/RBR-2cyp7c/.
has issue date	2020-08-07(xsd:dateTime)
bibo:doi	10.1186/s12887-020-02266-8
has license	cc-by
sha1sum (hex)	8c0559cc0cb46ff846995fd9d29ba02d86eb6bc0
schema:url	https://doi.org/10.1186/s12887-020-02266-8
resource representing a document's title	Colostrum oropharyngeal immunotherapy for very low birth weight preterm infants: protocol of an intervention study
has PubMed Central identifier	PMC7411269
schema:publication	BMC Pediatr
resource representing a document's body	covid:8c0559cc0cb46ff846995fd9d29ba02d86eb6bc0#body_text
is schema:about of	named entity 'newborns' named entity 'protocol' named entity 'reality' named entity 'treatment group' named entity 'oropharyngeal' named entity 'TREAT' named entity 'GROUPS' named entity '7TH' named entity 'binary' named entity 'colostrum' named entity 'birth weight' named entity 'facilitates' named entity 'Discussion' named entity 'participants' named entity 'unifies' named entity 'discharge' named entity 'control' named entity 'newborns' named entity 'aims' named entity 'decision-making' named entity 'born' named entity 'protocol' named entity 'neonatal unit' named entity 'hospital' named entity 'tissues' named entity 'groups' named entity 'public hospital' named entity 'oropharyngeal' named entity 'colostrum' named entity 'clinical progression' named entity 'mucosa' named entity 'chi-square test' named entity 'algorithm' named entity 'lymphoid tissues' named entity 'colostrum' named entity 'Colostrum' named entity 'preterm infants' named entity 'colostrum' named entity 'enteral nutrition' named entity 'stratified analysis' named entity 'glomerular filtration rate' named entity 'oropharyngeal' named entity 'human milk' named entity 'follow-up' named entity 'Brazil' named entity '28 days' named entity 'preterm infants' named entity 'multivariate analysis' named entity 'milk production' named entity 'immunotherapy' named entity 'pneumothorax' named entity 'oxygen supplementation' named entity 'abdominal wall' named entity 'Human Milk Bank' named entity 'control group' named entity 'convulsions' named entity 'puerperium' named entity 'medical diagnosis' named entity 'HMB' named entity 'low birth weight' named entity 'medical diagnosis' named entity 'HMB' named entity 'organ' named entity 'ReBEC' named entity 'UEFS' named entity 'Fisher's exact test' named entity 'oxygen therapy' named entity 'continuous variable' named entity 'State University of Feira de Santana' named entity 'treatment and control groups' named entity 'mechanical ventilation' named entity 'irritability' named entity 'SAME'

Faceted Search & Find service v1.13.91 as of Mar 24 2020

Alternative Linked Data Documents: Sponger | ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3229 as of Jul 10 2020, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (94 GB total memory)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software