About: One family cluster of avian influenza A(H7N9) virus infection in Shandong, China

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About: One family cluster of avian influenza A(H7N9) virus infection in Shandong, China Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
has title	One family cluster of avian influenza A(H7N9) virus infection in Shandong, China
Creator	Zhang, Tao Yang, Lei Shu, Yuelong Bi, Zhenqiang Liu, Jun Li, Zhong Yang, Bin Sun, Lin Liu, Ti Song, Shaoxia Wang, Xianjun Xu, Aiqiang Zhang, Shengyang Ding, Shujun Pang, Bo Lei, Jie Li, Xiyan Bi, Zhenwang Jiang, Xiaolin Kou, Zengqiang Lu, Kaishun Pei, Yaowen Sun, Dapeng Wang, Jianxing Wang, Liansen Yuan, Qun
Source	PMC
abstract	BACKGROUND: The first case of human infection with avian influenza A (H7N9) virus was identified in March, 2013 and the new H7N9 virus infected 134 patients and killed 45 people in China as of September 30, 2013. Family clusters with confirmed or suspected the new H7N9 virus infection were previously reported, but the family cluster of H7N9 virus infection in Shandong Province was first reported. CASE PRESENTATION: A 36-year-old man was admitted to Zaozhuang City Hospital with progressive respiratory distress and suspicion of impending acute respiratory distress syndrome on April 21. The chest radiography revealed bilateral ground-glass opacities and pulmonary lesions. The second case, the first case’s 4 year old son, was admitted to the same hospital on April 28 with fever and multiple patchy shadows in the bilateral lungs. Both of the two cases were confirmed to infect with H7N9 virus by the results of real-time reverse transcriptase-polymerase-chain reaction (rRT-PCR), virus isolation and serum antibody titer. At the same time, one environment samples was detected positive for H7N9 virus in the living poultry market in Zaozhuang. The homologous analysis of the full genome sequence indicated that both viruses from the patients were almost genetically identical. The field epidemiology investigation showed that the two cases had no recognized exposure to poultry, but had the exposure to the environment. The second case had substantial unprotected close exposure to his ill father and developed symptoms seven days after his last contact with his father. After surgery, the index case and his son were discharged on May 16 and May 6, respectively. 11 close contacts of both patients were identified and tested negative both the throat swabs and the serum antibody. CONCLUSION: The infection of the index case probably resulted from contact with environmentally contaminated material. For the son, the probable infection source was from the index case during unprotected exposure, but the possibility from the environment or other sources could not be completely ruled out.
has issue date	2014-02-21(xsd:dateTime)
bibo:doi	10.1186/1471-2334-14-98
bibo:pmid	24559386
has license	cc-by
sha1sum (hex)	8dcff92cc42c8b9833396a1df1a6712dd1d3e8d5
schema:url	https://doi.org/10.1186/1471-2334-14-98
resource representing a document's title	One family cluster of avian influenza A(H7N9) virus infection in Shandong, China
has PubMed Central identifier	PMC3974040
has PubMed identifier	24559386
schema:publication	BMC Infect Dis
resource representing a document's body	covid:8dcff92cc42c8b9833396a1df1a6712dd1d3e8d5#body_text
is schema:about of	named entity 'H7N9' named entity '2013' named entity 'virus' named entity 'H7N9' named entity 'virus' named entity 'China' named entity 'infection' named entity 'killed' named entity 'suspected' named entity 'virus infection' named entity 'China' named entity 'H7N9' named entity 'Shandong Province' named entity 'virus infection' named entity 'poultry' named entity 'common cold' named entity 'April 23' named entity 'fever' named entity 'vegetable' named entity 'poultry farms' named entity 'H7N9' named entity 'virus' named entity 'common cold' named entity 'May 16' named entity 'index patient' named entity 'antibody' named entity 'index case' named entity 'H7N9' named entity 'poultry' named entity 'April 18' named entity 'virus' named entity 'H7N9' named entity 'Shandong' named entity 'H7N9' named entity 'May 6' named entity 'April 21' named entity 'Shandong' named entity 'serum' named entity 'virus' named entity 'Initial testing' named entity 'Shandong' named entity 'poultry' named entity 'H7N9' named entity 'fever' named entity 'index case' named entity 'ground-glass opacities' named entity 'index case' named entity 'antibodies' named entity 'index case' named entity 'pneumonia' named entity 'rRT-PCR' named entity 'Ibuprofen' named entity 'expectorate' named entity 'infection' named entity 'global public health' named entity 'H7N9'

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