About: Association between Cardiovascular Burden and Requirement of Intensive Care among Patients with Mild COVID-19

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About: Association between Cardiovascular Burden and Requirement of Intensive Care among Patients with Mild COVID-19 Goto Sponge NotDistinct Permalink

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Association between Cardiovascular Burden and Requirement of Intensive Care among Patients with Mild COVID-19
Creator	Jiang4, Md; Bilian Yu1, , Md; Chongqin Tan4, Md; Chuan Wen4, Md; Chuanhao Jiang4, Md; Hui Yang1, Md; Huilin Zhang4, Md; Jianjun Tang1, , Md; Kui Xiao4, Md; Li Zhu4, Msc; Li Md; Liang Tang1, , Md; Tao Tu1, Md; Weihong Zhu4, Md; Xinqun Hu1, Md; Xuping Li1, Md; Jiaxing Md; Yang Wang4, , Md; Yichao Xiao1, Md; Zhaowei Zhu1, Md; Zhenfei Fang1, Md; Zhongbiao Jiang4, Msc; Qiming Liu1, Shi Tai1, , Sun1,
source	MedRxiv
abstract	Background: Information regarding the impact of cardiovascular disease (CVD) on disease progression among patients with mild coronavirus disease 2019 (COVID-19) is limited. Methods: This study evaluated the association of underlying CVD with disease progression in patients with mild COVID-19. The primary outcome was the need to be transferred to intensive care due to disease progression. The patients were divided with and without CVD as well as stable and intensive care groups. Results: Of 332 patients with mild COVID-19, median age was 51 years (IQR, 40-59 years), and 200 (61.2%) were female. Of 48 (14.5%) patients with CVD, 23 (47.9%) progressed to severe disease status and required intensive care. Compared with patients without CVD, patients with CVD were older, and more likely to have fatigue, chest tightness, and myalgia. The rate of requiring intensive care was significantly higher among patients with CVD than in patients without CVD (47.92% vs. 12.4%; P<0.001). In subgroup analysis, rate of requiring intensive care was also higher among patients with either hypertension or coronary heart disease than in patients without hypertension or coronary heart disease. The multivariable regression model showed CVD served as an independent risk factor for intensive care (Odd ratio [OR], 2.652 [95% CI, 1.019-6.899]) after adjustment for various cofounders. Conclusions: Patients with mild COVID-19 complicating CVD in are susceptible to develop severe disease status and requirement for intensive care.
has issue date	2020-05-26(xsd:dateTime)
bibo:doi	10.1101/2020.05.25.20111757
has license	medrxiv
sha1sum (hex)	951da8d677756551776d448eca830fa4485457c5
schema:url	https://doi.org/10.1101/2020.05.25.20111757
resource representing a document's title	Association between Cardiovascular Burden and Requirement of Intensive Care among Patients with Mild COVID-19
resource representing a document's body	covid:951da8d677756551776d448eca830fa4485457c5#body_text
is schema:about of	named entity 'cardiovascular disease' named entity 'progression' named entity 'INFORMATION' named entity 'MILD' covid:arg/951da8d677756551776d448eca830fa4485457c5 named entity 'Intensive Care' named entity 'disease progression' named entity 'cardiovascular diseases' named entity 'Kaplan-Meier curves' named entity 'medRxiv' named entity 'preprint' named entity 'peripheral vascular disease' named entity 'coronary heart disease' named entity 'myocardial injury' named entity 'liver' named entity 'COVID-19' named entity 'medRxiv' named entity 'CVDs' named entity 'COVID' named entity 'coronary heart disease' named entity 'virus infections' named entity 'peer review' named entity 'COVID' named entity 'recall bias' named entity 'platelet count' named entity 'Wuhan' named entity 'SARS-CoV-2' named entity 'neutrophil' named entity 'medRxiv' named entity 'World Health Organization' named entity 'retrospective study' named entity 'emerging infectious diseases' named entity 'ACE2' named entity 'clinical practice' named entity 'clinical data' named entity 'public health' named entity 'Genetic sequencing' named entity 'Pneumonia' named entity 'CVD' named entity 'Institutional Review Board' named entity 'platelet count' named entity 'hospital discharge' named entity 'COVID' named entity 'preprint' named entity 'χ2 test' named entity 'hypertension' named entity 'biochemical' named entity 'informed consent' named entity 'hypertension' named entity 'medRxiv' named entity 'COVID' named entity 'preprint' named entity 'SARS-CoV-2' named entity 'preprint' named entity 'statistical analyses' named entity 'COVID-19' named entity 'SARS-CoV-2' named entity 'preprint' named entity 'COVID' named entity 'medRxiv' named entity 'preprint' named entity 'logistic regression' named entity 'clinical symptoms'

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