About: No impact of early real-time PCR screening for respiratory viruses on length of stay and use of antibiotics in elderly patients hospitalized with symptoms of a respiratory tract infection in a single center in Norway

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About: No impact of early real-time PCR screening for respiratory viruses on length of stay and use of antibiotics in elderly patients hospitalized with symptoms of a respiratory tract infection in a single center in Norway Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	No impact of early real-time PCR screening for respiratory viruses on length of stay and use of antibiotics in elderly patients hospitalized with symptoms of a respiratory tract infection in a single center in Norway
Creator	Bakke, P Bjorvatn, B Hagen, E Hernes, S Quarsten, H
source	Medline; PMC
abstract	We tested the hypothesis that the results of real-time polymerase chain reaction (PCR) analyses for respiratory viruses would reduce antibiotic treatment and length of stay in elderly patients hospitalized with respiratory infections. Within 24 h of hospital admission, a total of 922 patients aged ≥60 years were interviewed for symptoms of ongoing respiratory tract infection. Symptomatic patients were swabbed for oropharyngeal/nasopharyngeal presence of viral pathogens immediately by members of the study group. During a 2-month period, non-symptomatic volunteers among interviewed patients were swabbed as well (controls). Oropharyngeal/nasopharyngeal swabs were analyzed with real-time PCR for nine common respiratory viruses. A total of 147 out of 173 symptomatic patients and 56 non-symptomatic patients (controls) agreed to participate in the study. The patients were allocated to three cohorts: (1) symptomatic and PCR-positive (S/PCR+), (2) symptomatic and PCR-negative (S/PCR−), or (3) non-symptomatic and PCR-negative (control). There were no non-symptomatic patients with a positive PCR result. A non-significant difference in the frequency of empiric antibiotic administration was found when comparing the S/PCR+ to the S/PCR− cohort; 16/19 (84 %) vs. 99/128 (77 %) (χ(2) = 0.49). Antibiotic treatment was withdrawn in only two patients in the S/PCR+ cohort after receiving a positive viral diagnosis. The length of stay did not significantly differ between the S/PCR+ and the S/PCR− groups. We conclude that, at least in our general hospital setting, access to early viral diagnosis by real-time PCR had little impact on the antimicrobial treatment or length of hospitalization of elderly patients. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s10096-013-1963-0) contains supplementary material, which is available to authorized users.
has issue date	2013-09-04(xsd:dateTime)
bibo:doi	10.1007/s10096-013-1963-0
bibo:pmid	23999830
has license	no-cc
sha1sum (hex)	95b52ba175efece646939c3117621966fe6c9fb7
schema:url	https://doi.org/10.1007/s10096-013-1963-0
resource representing a document's title	No impact of early real-time PCR screening for respiratory viruses on length of stay and use of antibiotics in elderly patients hospitalized with symptoms of a respiratory tract infection in a single center in Norway
has PubMed Central identifier	PMC7088319
has PubMed identifier	23999830
schema:publication	Eur J Clin Microbiol Infect Dis
resource representing a document's body	covid:95b52ba175efece646939c3117621966fe6c9fb7#body_text
is schema:about of	named entity 'LENGTH OF STAY' named entity 'symptoms' named entity 'period' named entity 'PCR' named entity 'real-time PCR' named entity 'access' named entity 'SYMPTOMS' named entity 'IMPACT' named entity 'LITTLE' named entity 'OUR' named entity 'SWABBED' named entity 'WITHDRAWN' named entity 'VOLUNTEERS' named entity 'COMMON' named entity 'DID' named entity 'COHORT' named entity '283' covid:arg/95b52ba175efece646939c3117621966fe6c9fb7 named entity 'RESPIRATORY VIRUSES' named entity '28S' named entity 'LENGTH OF STAY' named entity 'ELDERLY PATIENTS' named entity 'HOSPITAL ADMISSION' named entity 'SYMPTOMS' named entity 'GROUPS' named entity 'POSITIVE' named entity 'ANALYZED' named entity 'PATIENTS' named entity 'HYPOTHESIS' named entity 'MONTH' named entity 'SYMPTOMATIC' named entity 'RESPIRATORY TRACT INFECTION' named entity 'REDUCE' named entity 'STUDY' named entity 'USE OF' named entity 'SCREENING' named entity 'PCR' named entity 'SETTING' named entity 'ELDERLY PATIENTS' named entity 'CENTER' named entity 'HOSPITALIZED' named entity 'EARLY' named entity 'REAL-TIME POLYMERASE CHAIN REACTION' named entity 'SWABS' named entity 'FREQUENCY' named entity 'OROPHARYNGEAL' named entity 'RESPIRATORY VIRUSES' named entity 'AGED' named entity 'TESTED' named entity 'RESPIRATORY INFECTIONS' named entity 'ONGOING' named entity 'RESPIRATORY TRACT INFECTION' named entity 'DIAGNOSIS' named entity 'YEARS' named entity 'IMPACT' named entity 'TO PARTICIPATE' named entity 'ANTIBIOTIC ADMINISTRATION' named entity 'HOSPITALIZED' named entity 'ANTIBIOTIC TREATMENT' named entity 'CONCLUDE' named entity '2884' named entity 'RECEIVING' named entity 'LENGTH' named entity '282' named entity 'SINGLE' named entity 'NORWAY' named entity 'PERIOD' named entity 'RESULT' named entity 'COHORTS' named entity 'DIFFERENCE' named entity 'PRESENCE OF' named entity 'RESULTS' named entity 'NON-' named entity 'EARLY' named entity 'NASOPHARYNGEAL' named entity 'VIRAL PATHOGENS' named entity 'EMPIRIC'

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