About: Morphology Remodeling and Selective Autophagy of Intracellular Organelles during Viral Infections

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Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Morphology Remodeling and Selective Autophagy of Intracellular Organelles during Viral Infections
Creator	Ding, Chan Sun, Yingjie Ren, Shanhui
source	Medline; PMC
abstract	Viruses have evolved different strategies to hijack subcellular organelles during their life cycle to produce robust infectious progeny. Successful viral reproduction requires the precise assembly of progeny virions from viral genomes, structural proteins, and membrane components. Such spatial and temporal separation of assembly reactions depends on accurate coordination among intracellular compartmentalization in multiple organelles. Here, we overview the rearrangement and morphology remodeling of virus-triggered intracellular organelles. Focus is given to the quality control of intracellular organelles, the hijacking of the modified organelle membranes by viruses, morphology remodeling for viral replication, and degradation of intracellular organelles by virus-triggered selective autophagy. Understanding the functional reprogram and morphological remodeling in the virus-organelle interplay can provide new insights into the development of broad-spectrum antiviral strategies.
has issue date	2020-05-23(xsd:dateTime)
bibo:doi	10.3390/ijms21103689
bibo:pmid	32456258
has license	cc-by
sha1sum (hex)	966e032e292e7a6952c4db3633d89cbf9d66ca2a
schema:url	https://doi.org/10.3390/ijms21103689
resource representing a document's title	Morphology Remodeling and Selective Autophagy of Intracellular Organelles during Viral Infections
has PubMed Central identifier	PMC7279407
has PubMed identifier	32456258
schema:publication	Int J Mol Sci
resource representing a document's body	covid:966e032e292e7a6952c4db3633d89cbf9d66ca2a#body_text
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