About: Imaging manifestations and pathological analysis of severe pneumonia caused by human infected avian influenza (H7N9)()

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About: Imaging manifestations and pathological analysis of severe pneumonia caused by human infected avian influenza (H7N9)() Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Imaging manifestations and pathological analysis of severe pneumonia caused by human infected avian influenza (H7N9)()
Creator	Yuan, Jing Liu, Ying-Xia Lu, Pu-Xuan Li, Jing-Jing Zeng, Zheng Chen, De-Ming Huang, Xiang-Rong Le, Xiao-Hua Li, Guo-Bao Zhou, Bo-Ping
source	Elsevier; Medline; PMC
abstract	OBJECTIVE: To investigate the imaging and pathological findings of severe pneumonia caused by human infected avian influenza (H7N9), and therefore to further understand and improve diagnostic accuracy of severe pneumonia caused by human infected avian influenza (H7N9). METHODS: The relevant clinical and imaging data of 19 cases, including 10 males and 9 females, with pneumonia caused by human infected avian influenza (H7N9) was retrospectively analyzed. One of the cases had received percutaneous lung biopsy, with the clinical, imaging and pathological changes possible to be analyzed. RESULTS: The lesions were mainly located at lower lobes and dorsal of lungs, involving multiple lobes and segments. Ground-glass opacities and/or pulmonary opacities were the more often imaging manifestations of severe pneumonia caused by human infected avian influenza (H7N9) in early and evolving phases (19/19,100%). By biopsy following percutaneous lung puncture, exudation of slurry, cellulose, RBC and neutrophils, formation of hyaline membrane, squamous metaplasia and organizing exudates were observable at the alveolar space. Some of alveoli collapsed, and some responded to show compensatory emphysema. CONCLUSION: The imaging features of severe pneumonia caused by human infected avian influenza (H7N9) include obvious ground-glass opacity and pulmonary consolidation, mainly at lower lobes and dorsal of lungs, with rapid changes. The cross-analysis of imaging and pathology preliminary can elucidate the pathological mechanisms of ground-glass opacities and pulmonary consolidation of severe pneumonia. Such an intensive study is beneficial to prompt clinicians to observe and evaluate the progress of the disease. In addition, it is also in favor of managing the symptoms and reducing the mortality rate.
has issue date	2015-03-02(xsd:dateTime)
bibo:doi	10.1016/j.jrid.2015.02.003
bibo:pmid	32289065
has license	no-cc
sha1sum (hex)	97aef3e3fc062de1cd816862cf5f883046088468
schema:url	https://doi.org/10.1016/j.jrid.2015.02.003
resource representing a document's title	Imaging manifestations and pathological analysis of severe pneumonia caused by human infected avian influenza (H7N9)()
has PubMed Central identifier	PMC7104100
has PubMed identifier	32289065
schema:publication	Radiol Infect Dis
resource representing a document's body	covid:97aef3e3fc062de1cd816862cf5f883046088468#body_text
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