About: The 2b protein as a minor structural component of PRRSV

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	The 2b protein as a minor structural component of PRRSV
Creator	Christopher-Hennings, Jane Nelson, Eric Yoon, Kyoung-Jin Fang, Ying Lawson, Steven Wu, Wai-Hong Rowland, Raymond
source	Elsevier; Medline; PMC
abstract	Abstract Porcine reproductive and respiratory syndrome virus (PRRSV) ORF2 contains an internal ORF that codes for a small non-glycosylated protein known as 2b. Previous work had identified the presence of a 10kDa 2b protein in virus-infected cells and the induction of an anti-2b response in PRRSV-infected pigs, as well as a possible association of 2b with the virion (Wu et al., 2001, Virology 287:183–191). In this study, we utilized two experimental approaches, including the use of a 2b peptide-specific monoclonal antibody, to demonstrate that the PRRSV 2b protein is an integral component of the PRRSV virion. This study suggests that 2b in PRRSV is similar to the E protein in EAV and forms a minor structural component of the virion.
has issue date	2005-12-31(xsd:dateTime)
bibo:doi	10.1016/j.virusres.2005.06.014
bibo:pmid	16095746
has license	els-covid
sha1sum (hex)	97e1eff6dc723a31092e3d16f683de0d93efff0a
schema:url	https://doi.org/10.1016/j.virusres.2005.06.014
resource representing a document's title	The 2b protein as a minor structural component of PRRSV
has PubMed Central identifier	PMC7127422
has PubMed identifier	16095746
schema:publication	Virus Research
resource representing a document's body	covid:97e1eff6dc723a31092e3d16f683de0d93efff0a#body_text
is schema:about of	named entity 'PRRSV' named entity 'Previous' named entity 'A MINOR' named entity 'KNOWN' named entity 'INTERNAL' named entity 'ORF2' named entity 'PEPTIDE' named entity 'EXPERIMENTAL' named entity 'EAV' named entity 'INCLUDING' named entity '287' named entity 'PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS' named entity 'FORMS' named entity 'PIGS' named entity 'INTEGRAL' named entity 'WORK' named entity '2B PROTEIN' named entity 'COMPONENT' named entity 'CELLS' named entity 'ASSOCIATION' named entity 'GLYCOSYLATED PROTEIN' named entity 'A MINOR' named entity 'PRESENCE OF' named entity '191' named entity 'STUDY' named entity 'INDUCTION' named entity 'STRUCTURAL COMPONENT' named entity 'STRUCTURAL COMPONENT' named entity 'VIRUS' named entity 'PROTEIN ' named entity 'E PROTEIN' named entity 'MONOCLONAL ANTIBODY' named entity 'APPROACHES' named entity 'VIROLOGY' named entity 'PROTEIN ' named entity 'SPECIFIC' named entity 'INFECTED' named entity 'ORF' named entity 'NON-' named entity 'PREVIOUS' named entity 'KDA' named entity 'USE OF' named entity 'VIRION' named entity 'IDENTIFIED' named entity 'CODES' named entity 'SMALL' named entity 'CONTAINS' named entity 'SIMILAR' named entity '2B PROTEIN' named entity 'POSSIBLE' named entity 'RESPONSE' named entity 'reproductive' named entity 'protein' named entity 'This' named entity 'ORF2' named entity 'protein' named entity '2001' named entity 'protein' named entity 'PRRSV' named entity 'ORF2' named entity 'monoclonal antibody' named entity 'peptide' named entity 'protein' named entity 'ORF' named entity 'kDa' named entity 'protein' named entity 'glycosylated' named entity 'serum' named entity 'PRRSV' named entity 'protein' named entity 'macrophages' named entity 'virion' named entity 'methionine' named entity 'gradient centrifugation' named entity 'structural proteins'

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