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About:
Follow-up study of the pulmonary function and related physiological characteristics of COVID-19 survivors three months after recovery
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An Entity of Type :
schema:ScholarlyArticle
, within Data Space :
wasabi.inria.fr
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document(s)
Type:
Academic Article
research paper
schema:ScholarlyArticle
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type
Academic Article
research paper
schema:ScholarlyArticle
isDefinedBy
Covid-on-the-Web dataset
has title
Follow-up study of the pulmonary function and related physiological characteristics of COVID-19 survivors three months after recovery
Creator
Luo, Hong
Gao, Yan-Feng
Jia, Jun-Li
Li, Li-Ming
Li, Qing-Quan
Mao, Hong-Li
Shang, Yao-Min
Song, Wen-Bin
Xie, Hua
Xu, Ai-Guo
Xu, Qin-Fu
Yanfeng Gao,
Zhao, Yu-Miao
Zhou, Xiu-Man
topic
covid:982e5ec67502d726069c8fdbe0296621250269be#this
Source
Elsevier; Medline; PMC
abstract
BACKGROUND: The long-term pulmonary function and related physiological characteristics of COVID-19 survivors have not been studied in depth, thus many aspects are not understood. METHODS: COVID-19 survivors were recruited for high resolution computed tomography (HRCT) of the thorax, lung function and serum levels of SARS-CoV-2 IgG antibody tests 3 months after discharge. The relationship between the clinical characteristics and the pulmonary function or CT scores were investigated. FINDINGS: Fifty-five recovered patients participated in this study. SARS-CoV-2 infection related symptoms were detected in 35 of them and different degrees of radiological abnormalities were detected in 39 patients. Urea nitrogen concentration at admission was associated with the presence of CT abnormalities (P = 0.046, OR 7.149, 95% CI 1.038 to 49.216). Lung function abnormalities were detected in 14 patients and the measurement of D-dimer levels at admission may be useful for prediction of impaired diffusion defect (P = 0.031, OR 1.066, 95% CI 1.006 to 1.129). Of all the subjects, 47 of 55 patients tested positive for SARS-CoV-2 IgG in serum, among which the generation of Immunoglobulin G (IgG) antibody in female patients was stronger than male patients in infection rehabilitation phase. INTERPRETATION: Radiological and physiological abnormalities were still found in a considerable proportion of COVID-19 survivors without critical cases 3 months after discharge. Higher level of D-dimer on admission could effectively predict impaired DLCO after 3 months discharge. It is necessary to follow up the COVID-19 patients to appropriately manage any persistent or emerging long-term sequelae. FUNDING: Key Scientific Research Projects of Henan Higher Education Institutions
has issue date
2020-07-15
(
xsd:dateTime
)
bibo:doi
10.1016/j.eclinm.2020.100463
bibo:pmid
32838236
has license
no-cc
sha1sum (hex)
982e5ec67502d726069c8fdbe0296621250269be
schema:url
https://doi.org/10.1016/j.eclinm.2020.100463
resource representing a document's title
Follow-up study of the pulmonary function and related physiological characteristics of COVID-19 survivors three months after recovery
has PubMed Central identifier
PMC7361108
has PubMed identifier
32838236
schema:publication
EClinicalMedicine
resource representing a document's body
covid:982e5ec67502d726069c8fdbe0296621250269be#body_text
is
http://vocab.deri.ie/void#inDataset
of
https://covidontheweb.inria.fr:4443/about/id/http/ns.inria.fr/covid19/982e5ec67502d726069c8fdbe0296621250269be
is
schema:about
of
named entity 'positive'
named entity 'IgG'
named entity 'persistent'
named entity 'detected'
named entity 'measurement'
named entity 'antibody'
named entity 'patients'
named entity 'Methods'
named entity 'admission'
named entity 'COVID-19'
named entity 'serum'
named entity 'proportion'
named entity 'degrees'
named entity 'patients'
named entity 'infection'
named entity 'presence'
named entity 'survivors'
named entity 'Immunoglobulin G'
named entity 'SARS-CoV-2'
named entity 'antibody'
named entity 'prediction'
named entity '95% CI'
named entity 'Background'
named entity 'male'
named entity 'SARS-CoV-2'
named entity 'nitrogen'
named entity 'Lung function'
named entity 'thorax'
named entity 'COVID'
named entity 'DLCO'
named entity 'COVID'
named entity 'infection'
named entity 'IgG antibody'
named entity 'COVID-19'
named entity 'D-dimer'
named entity 'antibody'
named entity 'pulmonary function'
named entity 'COVID'
named entity 'COVID'
named entity 'COVID-19'
named entity 'radiographic'
named entity 'ground glass opacity'
named entity 'gastrointestinal'
named entity 'Affiliated Hospital'
named entity 'pulmonary diseases'
named entity 'COVID'
named entity 'SARS'
named entity 'olfactory'
named entity 'urea'
named entity 'centrifugation'
named entity 'pulmonary diffusion'
named entity 'hemoglobin'
named entity 'GI tract'
named entity 'SARS-CoV-1'
named entity 'gustatory'
named entity 'epidemiological'
named entity 'COVID-19'
named entity 'COVID'
named entity 'SARS-CoV-2'
named entity 'medical history'
named entity 'urea'
named entity 'SARS-CoV-2'
named entity 'Siemens'
named entity 'pulmonary function'
named entity 'protein metabolism'
named entity 'CXR'
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