About: Epidemiology and clinical outcomes of community-acquired pneumonia in adult patients in Asian countries: a prospective study by the Asian network for surveillance of resistant pathogens

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About: Epidemiology and clinical outcomes of community-acquired pneumonia in adult patients in Asian countries: a prospective study by the Asian network for surveillance of resistant pathogens Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Epidemiology and clinical outcomes of community-acquired pneumonia in adult patients in Asian countries: a prospective study by the Asian network for surveillance of resistant pathogens
Creator	Tong, Zhaohui Liu, Jien-Wei Wang, Qingtao Kang, Cheol-In Kim, Yeon-Sook Song, Jae-Hoon Tan, Ban-Hock Chang, Hyun-Ha Huang, Shao-Guang Jung, Sook-In Lalitha, M.K. So, Thomas Carlos, Celia Chung, Doo Kim, Choon Kim, Shin Oh, Won Peck, Kyong Van, Pham Yeom, Joon Ko, Kwan
source	PMC
abstract	Appropriate antimicrobial treatment of community-acquired pneumonia (CAP) should be based on the distribution of aetiological pathogens, antimicrobial resistance of major pathogens, clinical characteristics and outcomes. We performed a prospective observational study of 955 cases of adult CAP in 14 hospitals in eight Asian countries. Microbiological evaluation to determine etiological pathogens as well as clinical evaluation was performed. Bronchopulmonary disease (29.9%) was the most frequent underlying disease, followed by cardiovascular diseases (19.9%), malignancy (11.7%) and neurological disorder (8.2%). Streptococcus pneumoniae (29.2%) was the most common isolate, followed by Klebsiella pneumoniae (15.4%) and Haemophilus influenzae (15.1%). Serological tests were positive for Mycoplasma pneumoniae (11.0%) and Chlamydia pneumoniae (13.4%). Only 1.1% was positive for Legionella pneumophila by urinary antigen test. Of the pneumococcal isolates, 56.1% were resistant to erythromycin and 52.6% were not susceptible to penicillin. Seventeen percent of CAP had mixed infection, especially S. pneumoniae with C. pneumoniae. The overall mortality rate was 7.3%, and nursing home residence, mechanical ventilation, malignancy, cardiovascular diseases, respiratory rate > 30/min and hyponatraemia were significant independent risk factors for mortality by multivariate analysis (P < 0.05). The current data provide relevant information about pathogen distribution and antimicrobial resistance of major pathogens of CAP as well as clinical outcomes of illness in Asian countries.
has issue date	2007-12-26(xsd:dateTime)
bibo:doi	10.1016/j.ijantimicag.2007.09.014
bibo:pmid	18162378
has license	no-cc
schema:url	https://doi.org/10.1016/j.ijantimicag.2007.09.014
resource representing a document's title	Epidemiology and clinical outcomes of community-acquired pneumonia in adult patients in Asian countries: a prospective study by the Asian network for surveillance of resistant pathogens
has PubMed Central identifier	PMC7134693
has PubMed identifier	18162378
schema:publication	Int J Antimicrob Agents
resource representing a document's body	covid:PMC7134693#body_text
is schema:about of	named entity 'Asian network' named entity 'acute infection' named entity 'co-morbid' named entity 'Chonnam National University' named entity 'amoxicillin/clavulanic acid' named entity 'Infectious Diseases' named entity 'macrolides' named entity 'serological' named entity 'WBC' named entity 'Asian' named entity 'antimicrobial therapy' named entity 'mixed infections' named entity 'sputum' named entity 'serological' named entity 'blood cultures' named entity 'Drug-Resistant' named entity 'S. pneumoniae' named entity 'Antimicrobial agents' named entity 'Multivariate analysis' named entity 'cefuroxime' named entity 'pathogens' named entity 'penicillin' named entity 'standard deviation' named entity 'clinical characteristics' named entity 'erythromycin' named entity 'China' named entity 'pneumonia' named entity 'blood cultures' named entity 'Pseudomonas aeruginosa' named entity 'modern medicine' named entity 'penicillin' named entity 'PaO2' named entity 'pleural fluid' named entity 'Hong Kong' named entity 'aetiology' named entity 'France' named entity 'hypoxaemia' named entity 'Asian' named entity 'macrolides' named entity 'bacterial pathogens' named entity 'confounding variables' named entity 'pneumonia' named entity 'risk factors' named entity 'microbiology' named entity 'clinical practice' named entity 'South Korea' named entity 'CAP' named entity 'WBCs' named entity 'India' named entity 'mmHg' named entity 'pathogens' named entity 'Student's t-test' named entity 'Philippines' named entity 'Asian' named entity 'bacterial pathogens' named entity 'C. pneumoniae' named entity 'Pathogen' named entity 'Antimicrobial susceptibility tests' named entity 'ciprofloxacin' named entity 'antimicrobial' named entity 'IgM' named entity 'risk factors'

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