About: Infecciones previas o coincidentes con la sospecha de enfermedad de Kawasaki ¿debemos cambiar nuestra actitud?()

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type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Infecciones previas o coincidentes con la sospecha de enfermedad de Kawasaki ¿debemos cambiar nuestra actitud?()
Creator	Calvo, Cristina Antón-López, Jordi Fernández-Cooke, Elisa Sánchez-Manubens, Judith Barrios Tascón, Ana Daniel, Carlos Lozano, Grasa
source	Elsevier; PMC
abstract	INTRODUCTION: Kawasaki disease (KD) is a multisystem vasculitis associated with coronary artery abnormalities. Infections could be a trigger of the inflammation. The main aim of this study was to describe the presence of infections in children with KD, and to analyse the clinical characteristics and the presence of coronary abnormalities in these cases. PATIENTS AND METHODS: A retrospective study was performed within the Kawasaki Diseases Network (KAWA-RACE (2011-2016). An analysis was performed that included patients with positive microbiological findings (PMF) during the acute phase, as well as those with a previous recent infection (PRI) during the 4 weeks preceding KD diagnosis. RESULTS: The study included total of 621 children with KD, with PMF being found in 101 (16.3%) patients, and a PRI in 107 (17.2%). Significantly less echocardiographic abnormalities were found in the in the group with a PRI, when compared to those without a PRI (23 vs. 35%, P = .01) and also a lower proportion of overall coronary artery lesions (16 vs. 25%, P = .054). No significant differences were found in the proportion of aneurysms in either of these groups (PRI or PMF) when compared to those without infection. CONCLUSIONS: In the present study, no differences were found in the incidence of coronary aneurysms in either of the groups, with or without PRI or PMF. Therefore, if KD is suspected, appropriate treatment should be started despite having a confirmed infection.
has issue date	2018-08-01(xsd:dateTime)
bibo:doi	10.1016/j.anpedi.2018.06.017
bibo:pmid	30077502
has license	no-cc
sha1sum (hex)	a1fa38567b670b9896eea1af116231b5a4c9913d
schema:url	https://doi.org/10.1016/j.anpedi.2018.06.017
resource representing a document's title	Infecciones previas o coincidentes con la sospecha de enfermedad de Kawasaki ¿debemos cambiar nuestra actitud?()
has PubMed Central identifier	PMC7105073
has PubMed identifier	30077502
schema:publication	An Pediatr (Barc)
resource representing a document's body	covid:a1fa38567b670b9896eea1af116231b5a4c9913d#body_text
is schema:about of	named entity 'ENFERMEDAD' named entity 'KAWASAKI' named entity 'infección' named entity 'infección' named entity 'el 10' named entity 'adenovirus' named entity 'tabla' named entity 'infección' named entity 'puede ser' named entity 'gastroenteritis' named entity 'infección' named entity 'mismo' named entity 'infección' named entity 'pericarditis' named entity '15 años' named entity 'enterovirus' named entity 'GWAS' named entity 'la respuesta' named entity 'blandas' named entity 'infección' named entity 'infección' named entity 'la red' named entity 'tabla' named entity 'infección' named entity 'infección' named entity 'otitis media' named entity 'hace' named entity 'origen' named entity 'infección' named entity 'enterovirus' named entity 'hacer' named entity 'como' named entity 'KAWA' named entity 'infección' named entity 'REDcap' named entity 'infección' named entity 'la fiebre' named entity 'adenovirus' named entity 'adenovirus' named entity '2, 7' named entity 'adenovirus' named entity 'La alteración' named entity 'infección' named entity 'tabla' named entity 'vasculitis' named entity 'gastroenteritis' named entity 'Tabla' named entity 'exacto' named entity 'chikungunya' named entity 'parainfluenza' named entity 'infección' named entity 'la Sociedad' named entity 'igual' named entity 'infección' named entity 'la fiebre' named entity 'aguda' named entity 'SPSS' named entity 'Infección' named entity 'infección' named entity 'adenovirus' named entity 'infección' named entity 'misma' named entity 'el 16'
is part of of	covid:a1fa38567b670b9896eea1af116231b5a4c9913d#body_text Infecciones previas o coincidentes con la sospecha de enfermedad de Kawasaki ¿debemos cambiar nuestra actitud?() INTRODUCTION: Kawasaki disease (KD) is a multisystem vasculitis associated with coronary artery abnormalities. Infections could be a trigger of the inflammation. The main aim of this study was to describe the presence of infections in children with KD, and to analyse the clinical characteristics and the presence of coronary abnormalities in these cases. PATIENTS AND METHODS: A retrospective study was performed within the Kawasaki Diseases Network (KAWA-RACE (2011-2016). An analysis was performed that included patients with positive microbiological findings (PMF) during the acute phase, as well as those with a previous recent infection (PRI) during the 4 weeks preceding KD diagnosis. RESULTS: The study included total of 621 children with KD, with PMF being found in 101 (16.3%) patients, and a PRI in 107 (17.2%). Significantly less echocardiographic abnormalities were found in the in the group with a PRI, when compared to those without a PRI (23 vs. 35%, P = .01) and also a lower proportion of overall coronary artery lesions (16 vs. 25%, P = .054). No significant differences were found in the proportion of aneurysms in either of these groups (PRI or PMF) when compared to those without infection. CONCLUSIONS: In the present study, no differences were found in the incidence of coronary aneurysms in either of the groups, with or without PRI or PMF. Therefore, if KD is suspected, appropriate treatment should be started despite having a confirmed infection.

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