About: A novel feline norovirus in diarrheic cats

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About: A novel feline norovirus in diarrheic cats Goto Sponge NotDistinct Permalink

An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	A novel feline norovirus in diarrheic cats
Creator	Martella, Vito Marsilio, Fulvio Melegari, Irene Robetto, Serena Lanave, Gianvito Aste, Giovanni Sarchese, Vittorio Martino, Barbara Profio, Federica Cafiero, Maria
source	Elsevier; Medline; PMC
abstract	Abstract By screening a collection of fecal samples from young cats housed in three different shelters in South Italy, noroviruses (NoVs) were found in 3/48 (6.2%) specimens of animals with enteritis signs while they were not detected in samples collected from healthy cats (0/57). Upon sequence analysis of the short RNA-dependent RNA polymerase (RdRp) region, the three strains displayed the highest nucleotide (nt) and amino acid (aa) identities to the prototype GIV.2 strain lion/Pistoia/387/06/ITA (91.0–93.0% nt and 97.0–98.0% aa). The sequence of ~3.4-kb portion at the 3′ end of the genome of a NoV strain, TE/77-13/ITA, was determined. In the full-length ORF2, encoding the VP1 capsid protein, the virus was genetically closest to the canine GVI.2 NoV strains C33/Viseu/2007/PRT and FD53/2007/ITA (81.0–84.0% nt and 93.0–94.0% aa identities), suggesting a recombination nature, with the cross-over site being mapped to the ORF1-ORF2 junction. Based on the full-length VP1 amino acid sequence, we classified the novel feline NoV, together with the canine strains Viseu and FD53, as a genotype 2, within the genogroup GVI. These findings indicate that, as observed for GIV NoV, GVI strains may infect both the canine and feline host. Unrestricted circulation of NoV strains in small carnivores may provide the basis for quick genetic diversification of these viruses by recombination. Interspecies circulation of NoVs in pets must also be considered when facing outbreaks of enteric diseases in these animals.
has issue date	2016-03-31(xsd:dateTime)
bibo:doi	10.1016/j.meegid.2015.12.019
bibo:pmid	26739218
has license	els-covid
sha1sum (hex)	a2baa4e07df066fb5c7cd8cf4445966cfcdfcf30
schema:url	https://doi.org/10.1016/j.meegid.2015.12.019
resource representing a document's title	A novel feline norovirus in diarrheic cats
has PubMed Central identifier	PMC7185403
has PubMed identifier	26739218
schema:publication	Infection, Genetics and Evolution
resource representing a document's body	covid:a2baa4e07df066fb5c7cd8cf4445966cfcdfcf30#body_text
is schema:about of	named entity 'FELINE' named entity 'CARNIVORES' named entity 'DISPLAYED' named entity 'DETERMINED' named entity 'JUNCTION' named entity 'CIRCULATION' named entity 'NATURE' named entity 'INFECT' named entity 'ANIMALS' named entity 'ENTERITIS' named entity 'HOST' named entity 'THESE' named entity 'GENOME' covid:arg/a2baa4e07df066fb5c7cd8cf4445966cfcdfcf30 named entity 'NOVEL' named entity 'PROVIDE' named entity 'AMINO ACID' named entity 'UNRESTRICTED' named entity 'SEQUENCE' named entity 'CONSIDERED' named entity 'FELINE' named entity 'CROSS-OVER' named entity 'C33' named entity 'CATS' named entity 'RNA-DEPENDENT RNA POLYMERASE' named entity 'SPECIMENS' named entity 'OUTBREAKS' named entity 'ENTERIC' named entity 'DISEASES' named entity 'FECAL' named entity '3.4' named entity 'SIGNS' named entity 'SHELTERS' named entity 'OBSERVED' named entity 'NOV' named entity 'NOROVIRUSES' named entity 'CLASSIFIED' named entity 'PORTION' named entity 'CLOSEST' named entity 'VISEU' named entity 'HOUSED' named entity 'SOUTH' named entity 'REGION' named entity 'BEING' named entity 'GIV' named entity 'HEALTHY' named entity 'FOUND' named entity 'GENETIC DIVERSIFICATION' named entity 'IDENTITIES' named entity 'ORF2' named entity 'ITALY' named entity '80%' named entity 'VP1' named entity 'SHORT' named entity 'AMINO ACID SEQUENCE' named entity 'BASED' named entity 'BASIS' named entity 'VIRUS' named entity 'DIFFERENT' named entity 'NOROVIRUS' named entity 'CATS' named entity 'SEQUENCE ANALYSIS' named entity 'YOUNG' named entity 'HIGHEST' named entity 'CAPSID PROTEIN' named entity 'STRAINS' named entity 'SAMPLES' named entity 'MAPPED' named entity 'FINDINGS' named entity 'LION' named entity 'SITE' named entity 'PROTOTYPE'

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