About: AN AFFORDABLE ANTI-SARS-COV-2 SPIKE ELISA TEST FOR EARLY DETECTION OF IgG SEROCONVERSION SUITED FOR LARGE-SCALE SURVEILLANCE STUDIES IN LOW-INCOME COUNTRIES

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About: AN AFFORDABLE ANTI-SARS-COV-2 SPIKE ELISA TEST FOR EARLY DETECTION OF IgG SEROCONVERSION SUITED FOR LARGE-SCALE SURVEILLANCE STUDIES IN LOW-INCOME COUNTRIES Goto Sponge NotDistinct Permalink

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Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	AN AFFORDABLE ANTI-SARS-COV-2 SPIKE ELISA TEST FOR EARLY DETECTION OF IgG SEROCONVERSION SUITED FOR LARGE-SCALE SURVEILLANCE STUDIES IN LOW-INCOME COUNTRIES
Creator	Tanuri, Amilcar Vale, André Higa, Luiza Travassos, Leonardo Carvalho, Renato Castilho, Leda Galliez, Rafael Lima, Tulio Bozza, Vicente Castineiras, Terezinha Ferreira, Orlando Leitão, Isabela Marsili, Federico Monteiro, Fabio Nobrega, Alberto Rodrigues,
source	MedRxiv
abstract	We describe a cost-effective, scalable technology to produce SARS-COV-2 spike (S) protein based on stable expression in HEK293 cells, and its use to develop a highly specific and sensitive ELISA test. The assay allows early detection of anti-S IgG seroconversion and endpoint titers correlate with virus neutralization. The low-cost S-antigen production, together with sample collection by finger prick and dried blood spots, allowed the development of a half-dollar test that fits the urgent need for large-scale serological surveillance in low-income countries.
has issue date	2020-07-15(xsd:dateTime)
bibo:doi	10.1101/2020.07.13.20152884
has license	medrxiv
sha1sum (hex)	a601d4824a571e9ab1787a04eea7c9ee7c720677
schema:url	https://doi.org/10.1101/2020.07.13.20152884
resource representing a document's title	AN AFFORDABLE ANTI-SARS-COV-2 SPIKE ELISA TEST FOR EARLY DETECTION OF IgG SEROCONVERSION SUITED FOR LARGE-SCALE SURVEILLANCE STUDIES IN LOW-INCOME COUNTRIES
resource representing a document's body	covid:a601d4824a571e9ab1787a04eea7c9ee7c720677#body_text
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