About: Impact of the COVID-19 pandemic on hyperacute stroke treatment: experience from a comprehensive stroke centre in Singapore

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An Entity of Type : schema:ScholarlyArticle, within Data Space : wasabi.inria.fr associated with source document(s)

Attributes	Values
type	Academic Article research paper schema:ScholarlyArticle
isDefinedBy	Covid-on-the-Web dataset
title	Impact of the COVID-19 pandemic on hyperacute stroke treatment: experience from a comprehensive stroke centre in Singapore
Creator	Lee, M Sharma, Vijay Christopher, · Wong, Y Daniel, · David, · Tan, Y Ahmad, Aftab Benjamin, · Chan, Bernard Chua, Y Cross, Gail Goh, Yihui Khoo, Deborah Leonard, · Leow, Aloysius Paliwal, Prakash Yeo, L Chia, Magdalene Chin, Amanda Gopinathan, Anil Hung, Jennifer Quak, Zhixuan Yang, Cunli Yau, Ying-Wei Teoh, Chang-Chuan, · Chor, W Hock-Luen, · Lily, · Mingxue, · Raymond, · Seet, C Sibi, · Tang, K The, Ei
source	Medline; PMC
abstract	The Coronavirus disease 2019 (COVID-19) pandemic is rapidly evolving and affecting healthcare systems across the world. Singapore has escalated its alert level to Disease Outbreak Response System Condition (DORSCON) Orange, signifying severe disease with community spread. We aimed to study the overall volume of AIS cases and the delivery of hyperacute stroke services during DORSCON Orange. This was a single-centre, observational cohort study performed at a comprehensive stroke centre responsible for AIS cases in the western region of Singapore, as well as providing care for COVID-19 patients. All AIS patients reviewed as an acute stroke activation in the Emergency Department (ED) from November 2019 to April 2020 were included. System processes timings, treatment and clinical outcome variables were collected. We studied 350 AIS activation patients admitted through the ED, 206 (58.9%) pre- and 144 during DORSCON Orange. Across the study period, number of stroke activations showed significant decline (p = 0.004, 95% CI 6.513 to − 2.287), as the number of COVID-19 cases increased exponentially, whilst proportion of activations receiving acute recanalization therapy remained stable (p = 0.519, 95% CI − 1.605 to 2.702). Amongst AIS patients that received acute recanalization therapy, early neurological outcomes in terms of change in median NIHSS at 24 h (-4 versus -4, p = 0.685) were largely similar between the pre- and during DORSCON orange periods. The number of stroke activations decreased while the proportion receiving acute recanalization therapy remained stable in the current COVID-19 pandemic in Singapore. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s11239-020-02225-1) contains supplementary material, which is available to authorized users.
has issue date	2020-07-13(xsd:dateTime)
bibo:doi	10.1007/s11239-020-02225-1
bibo:pmid	32661758
has license	no-cc
sha1sum (hex)	a7528c1bbd8b034a26dc90b979d9ef7d0c8c475a
schema:url	https://doi.org/10.1007/s11239-020-02225-1
resource representing a document's title	Impact of the COVID-19 pandemic on hyperacute stroke treatment: experience from a comprehensive stroke centre in Singapore
has PubMed Central identifier	PMC7358288
has PubMed identifier	32661758
schema:publication	J Thromb Thrombolysis
resource representing a document's body	covid:a7528c1bbd8b034a26dc90b979d9ef7d0c8c475a#body_text
is schema:about of	named entity 'healthcare systems' named entity 'cases' named entity 'terms' named entity 'AIS' named entity 'cases' named entity 'centre' named entity '95% CI' named entity 'cohort study' named entity 'centre' named entity 'HEALTHCARE SYSTEMS' named entity 'COMMUNITY SPREAD' named entity '144' named entity 'INCLUDED' named entity 'CHANGE IN' named entity 'SYSTEM' named entity 'ACUTE STROKE' named entity 'PROVIDING' named entity 'RECEIVED' named entity 'PROPORTION' named entity 'SERVICES' named entity 'CONDITION' named entity 'PATIENTS' named entity 'OBSERVATIONAL' named entity 'PRE' named entity 'THERAPY' named entity 'SIGNIFICANT' named entity 'STROKE' named entity 'AFFECTING' named entity 'DECREASED' named entity 'NIHSS' named entity 'HYPERACUTE' named entity 'COVID-19' named entity '95% CI' named entity 'early' named entity 'AIS' named entity 'median' named entity 'Disease' named entity 'stroke' named entity 'disease' named entity 'NIHSS' named entity 'AIS' named entity 'acute' named entity 'Impact' named entity 'cohort study' named entity 'Singapore' named entity 'NIHSS'

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